SCHEMBL3199686

SCHEMBL3199686

C[CH]c1ccc(O)c(OC)c1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 2/20 0.72
ALDH1A1 P00352 2/20 0.69
HPGD P15428 2/20 0.69
TDP1 Q9NUW8 2/20 0.69
TRPA1 O75762 1/20 0.69
TRIM24 O15164 1/20 0.69
ALDH5A1 P51649 1/20 0.69
ABAT P80404 1/20 0.69
TRIM33 Q9UPN9 1/20 0.69
TTR P02766 1/20 0.65
NFE2L2 Q16236 3/20 0.62
ALOX5 P09917 3/20 0.61
CYP2D6 P10635 3/20 0.61
CYP1A2 P05177 3/20 0.61
NFKB1 P19838 2/20 0.61
HSD11B1 P28845 2/20 0.61
STAT3 P40763 2/20 0.61
NFKB2 Q00653 2/20 0.61
RELA Q04206 2/20 0.61
XDH P47989 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL671149 0.85 TTR (0.85) TYRALDH1A1HPGDTDP1TRPA1
SCHEMBL30807100 0.85 TTR (0.85) TYRALDH1A1HPGDTDP1TRPA1
SCHEMBL671150 0.85 TTR (0.85) TYRALDH1A1HPGDTDP1TRPA1
SCHEMBL17732299 0.85 TTR (0.85) TYRALDH1A1HPGDTDP1TRPA1
Cis/Trans-Isoeugenol SCHEMBL2463283 0.84 TYR (1.00) TYRALDH1A1HPGDTDP1TRPA1
Isoeugenol SCHEMBL29369838 0.84 TYR (1.00) TYRALDH1A1HPGDTDP1TRPA1
Isoeugenol SCHEMBL2463281 0.84 TYR (1.00) TYRALDH1A1HPGDTDP1TRPA1
Cis/Trans-Isoeugenol SCHEMBL57987 0.84 TYR (1.00) TYRALDH1A1HPGDTDP1TRPA1
Isoeugenol SCHEMBL300766 0.84 TYR (1.00) TYRALDH1A1HPGDTDP1TRPA1
Cis/Trans-Isoeugenol SCHEMBL29361918 0.84 TYR (1.00) TYRALDH1A1HPGDTDP1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240196852-A1 HYBRID PEPPER PLANT NAMED CAPTAIN HM.CLAUSE, INC. 2024-06-20 US disclosed
US-20240023509-A1 HYBRID PEPPER PLANT NAMED ALTAMURA HM.CLAUSE, INC. 2024-01-25 US disclosed
US-20240023508-A1 HYBRID PEPPER PLANT NAMED ALTATA HM.CLAUSE, INC. 2024-01-25 US disclosed
US-11845941-B2 Plants comprising a low copy number of Ri genes KNUD JEPSEN A/S (DK) 2023-12-19 US disclosed
US-20230371458-A1 PEPPER VARIETY NUN 70064 PPH NUNHEMS B.V. (NL) 2023-11-23 US disclosed
US-20230320308-A1 PEPPER VARIETY NUN 70062 PPH NUNHEMS B.V. (NL) 2023-10-12 US disclosed
US-20230189749-A1 HYBRID PEPPER PLANT NAMED AVERY HM.CLAUSE, INC. 2023-06-22 US disclosed
US-11388870-B2 Hybrid pepper plant named AWAKINO HM.CLAUSE, S.A.S. (FR) 2022-07-19 US disclosed
US-11324174-B2 Hybrid pepper plant named AKUMAL HM.CLAUSE, S.A.S. (FR) 2022-05-10 US disclosed
US-11234408-B2 Pepper variety NUN 89007 PPS NUNHEMS B.V. (NL) 2022-02-01 US disclosed
US-20120151622-A1 PHYTOPHTHORA RESISTANCE IN SWEET PEPPERS CLAUSE (FR) 2012-06-14 US disclosed
CN-101068464-B Method for producing PMMoV-resistant capsicum plants DE RUITER SEEDS R & D BV 2011-07-13 CN disclosed
US-20100035881-A1 WRINKLE-IMPROVING AGENT SHISEIDO COMPANY, LTD. (JP) 2010-02-11 US disclosed
EP-1941861-A1 WRINKLE-IMPROVING AGENT Shiseido Company, Limited (JP) 2008-07-09 EP disclosed
EP-1880711-A1 PARAKERATOSIS INHIBITOR, PORE-SHRINKING AGENT AND EXTERNAL COMPOSITION FOR SKIN Shiseido Company, Limited (JP) 2008-01-23 EP disclosed
CN-101068464-A Pmmov resistant capsicum plants DE RUITER SEEDS R & D BV (NL) 2007-11-07 CN disclosed
US-20070234441-A1 PMMOV RESISTANT CAPSICUM PLANTS DE RUITER SEEDS R&D B.V. (NL) 2007-10-04 US disclosed
EP-1804571-A2 PMMOV RESISTANT CAPSICUM PLANTS De Ruiter Seeds R&D B.V. (NL) 2007-07-11 EP disclosed
EP-1647182-A1 PMMoV resistant Capsicum plants De Ruiter Seeds R&D B.V. (NL) 2006-04-19 EP disclosed
WO-2006038794-A2 PMMOV RESISTANT CAPSIUM PLANTS DE RUITER SEEDS R & D B.V. (NL) 2006-04-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100035881-A1 WRINKLE-IMPROVING AGENT AAAS, GLA, COL14A1 TYR 84/4885ALDH1A1 1501/4885HPGD 1474/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.