SCHEMBL671149

SCHEMBL671149

COc1cc(/C=C/c2ccc(O)c(OC)c2)ccc1O

nearest known ligand 0.85

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.85
NFE2L2 Q16236 3/20 0.82
TYR P14679 2/20 0.81
ALOX5 P09917 3/20 0.79
APP P05067 8/20 0.77
CYP2D6 P10635 3/20 0.73
CYP1A2 P05177 2/20 0.73
NFKB1 P19838 2/20 0.73
HSD11B1 P28845 2/20 0.73
STAT3 P40763 2/20 0.73
NFKB2 Q00653 2/20 0.73
RELA Q04206 2/20 0.73
XDH P47989 1/20 0.73
ALDH1A1 P00352 2/20 0.71
HPGD P15428 2/20 0.71
TDP1 Q9NUW8 2/20 0.71
TRPA1 O75762 1/20 0.71
TRIM24 O15164 1/20 0.71
ALDH5A1 P51649 1/20 0.71
ABAT P80404 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL671150 1.00 TTR (0.85) TTRNFE2L2TYRALOX5APP
SCHEMBL17732299 1.00 TTR (0.85) TTRNFE2L2TYRALOX5APP
SCHEMBL30807100 1.00 TTR (0.85) TTRNFE2L2TYRALOX5APP
SCHEMBL18270545 0.94 TTR (0.77) TTRNFE2L2TYRALOX5APP
SCHEMBL25381427 0.92 TTR (0.80) TTRNFE2L2TYRALOX5APP
SCHEMBL13004148 0.92 TTR (1.00) TTRNFE2L2TYRALOX5APP
SCHEMBL14782177 0.92 TTR (1.00) TTRNFE2L2TYRALOX5APP
SCHEMBL9616786 0.92 TTR (0.80) TTRNFE2L2TYRALOX5APP
SCHEMBL5315843 0.92 TTR (0.80) TTRNFE2L2TYRALOX5APP
SCHEMBL28897116 0.92 TTR (0.80) TTRNFE2L2TYRALOX5APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117551258-B Biological source light response epoxy resin and preparation method thereof 西南石油大学 2024-03-15 CN claimed
CN-117603430-A Light response three-section shape memory polyurethane material and preparation method thereof 西南石油大学 2024-02-27 CN claimed
CN-117551258-A Biological source light response epoxy resin and preparation method thereof 西南石油大学 2024-02-13 CN claimed
CN-110563779-A jujube pit extract and extraction and separation method and application thereof 西北大学 2019-12-13 CN claimed
US-10287237-B1 Polymeric materials made from vanillin THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2019-05-14 US claimed
US-20150090252-A1 APPARATUS AND PROCESS FOR PASTEURIZATION OF SAP AND PRODUCT THEREOF FEDERATION DES PRODUCTEURS ACERICOLES DU QUEBEC (CA) 2015-04-02 US claimed
US-20130310332-A1 MAPLE TREE-DERIVED PRODUCTS AND USES THEREOF UNIVERSITY OF RHODE ISLAND (US) 2013-11-21 US claimed
US-20130267474-A1 NOVEL PHYTOCHEMICALS FROM EXTRACTS OF MAPLE SYRUPS AND MAPLE TREES AND USES THEREOF UNIVERSITY OF RHODE ISLAND (US) 2013-10-10 US claimed
WO-2012122639-A1 APPARATUS AND PROCESS FOR PASTEURIZATION OF SAP AND PRODUCT THEREOF FÉDÉRATION DES PRODUCTEURS ACÉRICOLES DU QUÉBEC (CA) 2012-09-20 WO claimed
WO-2012055010-A1 MAPLE TREE-DERIVED PRODUCTS AND USES THEREOF FÉDÉRATION DES PRODUCTEURS ACÉRICOLES DU QUÉBEC (CA) 2012-05-03 WO claimed
WO-2012021981-A1 NOVEL PHYTOCHEMICALS FROM EXTRACTS OF MAPLE SYRUPS AND MAPLE TREES AND USES THEREOF FÉDÉRATION DES PRODUCTEURS ACÉRICOLES DU QUÉBEC (CA) 2012-02-23 WO claimed
US-20080139650-A1 Fungicidally Active Polymer Dispersions And Use Thereof CELANESE EMULSIONS GMBH (DE) 2008-06-12 US claimed
CN-118664699-A Composition and method for improving performance of wood rotary friction welding test piece 中南林业科技大学 2024-09-20 CN disclosed
CN-117551258-B Biological source light response epoxy resin and preparation method thereof 西南石油大学 2024-03-15 CN disclosed
CN-117551258-B Biological source light response epoxy resin and preparation method thereof 西南石油大学 2024-03-15 CN disclosed
CN-117603430-A Light response three-section shape memory polyurethane material and preparation method thereof 西南石油大学 2024-02-27 CN disclosed
WO-2012021983-A1 SUGAR PLANT DERIVED BY-PRODUCTS AND METHODS OF PRODUCTION THEREOF FÉDÉRATION DES PRODUCTEURS ACÉRICOLES DU QUÉBEC (CA) 2012-02-23 WO disclosed
WO-2012021981-A1 NOVEL PHYTOCHEMICALS FROM EXTRACTS OF MAPLE SYRUPS AND MAPLE TREES AND USES THEREOF FÉDÉRATION DES PRODUCTEURS ACÉRICOLES DU QUÉBEC (CA) 2012-02-23 WO disclosed
US-20080139650-A1 Fungicidally Active Polymer Dispersions And Use Thereof CELANESE EMULSIONS GMBH (DE) 2008-06-12 US disclosed
US-5611889-A DISCOLORATION INHIBITION; BRIGHTENING; PAPERMAKING PULP AND PAPER RESEARCH INSTITUTE OF CANADA (CA) 1997-03-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10287237-B1 Polymeric materials made from vanillin VCL, PORCN, HVCN1 TTR 965/4885NFE2L2 1742/4885TYR 109/4885
US-20130267474-A1 NOVEL PHYTOCHEMICALS FROM EXTRACTS OF MAPLE SYRUPS AND MAPLE TREES AND USES THEREOF BPHL, OAT, PSAT1 TTR 2348/4885NFE2L2 236/4885TYR 582/4885
US-20080139650-A1 Fungicidally Active Polymer Dispersions And Use Thereof CBR3, CBR1, CYP3A4 TTR 2839/4885NFE2L2 3306/4885TYR 839/4885
US-20130310332-A1 MAPLE TREE-DERIVED PRODUCTS AND USES THEREOF FASN, NNT, MAPK7 TTR 1221/4885NFE2L2 3878/4885TYR 43/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.