Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10278534 | 1.00 | MEN1 (0.36) | MEN1KMT2AALDH1A1HTTGAA | |
| SCHEMBL14902699 | 0.82 | MEN1 (0.31) | MEN1KMT2AHTTGAA | |
| SCHEMBL319269 | 0.82 | MEN1 (0.31) | MEN1KMT2AHTTGAA | |
| SCHEMBL14891525 | 0.81 | MEN1 (0.35) | MEN1KMT2AALDH1A1HTTGAA | |
| SCHEMBL320562 | 0.81 | MEN1 (0.35) | MEN1KMT2AALDH1A1HTTGAA | |
| SCHEMBL1911227 | 0.81 | MEN1 (0.35) | MEN1KMT2AALDH1A1HTTGAA | |
| SCHEMBL1911116 | 0.78 | MEN1 (0.36) | MEN1KMT2AALDH1A1HTTGAA | |
| SCHEMBL14902769 | 0.78 | MEN1 (0.36) | MEN1KMT2AALDH1A1HTTGAA | |
| SCHEMBL1910806 | 0.77 | MEN1 (0.38) | MEN1KMT2AALDH1A1HTTGAA | |
| SCHEMBL319433 | 0.77 | MEN1 (0.38) | MEN1KMT2AALDH1A1HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590968-A1 | CYCLIC ETHER COMPOUNDS USEFUL AS KINASE INHIBITORS | Novartis AG (CH) | 2013-05-15 | — | — | EP | disclosed |
| WO-2012004217-A1 | CYCLIC ETHER COMPOUNDS USEFUL AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2012-01-12 | — | — | WO | disclosed |