Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH2 | P05091 | 20/20 | 1.00 |
| ▸ | MAOA | P21397 | 11/20 | 1.00 |
| ▸ | MAOB | P27338 | 11/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7752699 | 1.00 | ALDH2 (1.00) | ALDH2MAOAMAOB | |
| SCHEMBL320544 | 1.00 | ALDH2 (1.00) | ALDH2MAOAMAOB | |
| SCHEMBL320049 | 1.00 | ALDH2 (1.00) | ALDH2MAOAMAOB | |
| SCHEMBL8983987 | 0.91 | ALDH2 (0.84) | ALDH2MAOAMAOB | |
| SCHEMBL8983889 | 0.91 | ALDH2 (0.84) | ALDH2MAOAMAOB | |
| SCHEMBL4686444 | 0.89 | ALDH2 (1.00) | ALDH2MAOAMAOB | |
| SCHEMBL4684115 | 0.89 | ALDH2 (1.00) | ALDH2MAOAMAOB | |
| SCHEMBL4679869 | 0.89 | ALDH2 (1.00) | ALDH2MAOAMAOB | |
| SCHEMBL4683189 | 0.87 | ALDH2 (1.00) | ALDH2MAOAMAOB | |
| SCHEMBL5492489 | 0.87 | ALDH2 (1.00) | ALDH2MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3170499-A1 | TREATMENT FOR COCAINE ADDICTION | Tonix Pharmaceuticals, Inc. (US) | 2017-05-24 | — | — | EP | disclosed |
| EP-2611440-B1 | TREATMENT FOR COCAINE ADDICTION | TONIX PHARMACEUTICALS INC (US) | 2017-02-01 | — | — | EP | disclosed |
| US-8481599-B2 | Compositions and methods for increasing compliance with therapies using aldehyde dehydrogenase inhibitors and treating alcoholism | TONIX PHARMACEUTICALS INC. (US) | 2013-07-09 | — | — | US | disclosed |
| US-20130165511-A1 | TREATMENT FOR COCAINE ADDICTION | TONIX Pharmaceuticals Holding Corp (US) | 2013-06-27 | — | — | US | disclosed |
| US-20120101154-A1 | COMPOSITIONS AND METHODS FOR INCREASING COMPLIANCE WITH THERAPIES USING ALDEHYDE DEHYDROGENASE INHIBITORS AND TREATING ALCOHOLISM | Tonix Pharmaceuticals, Inc. (US) | 2012-04-26 | — | — | US | disclosed |
| US-8093300-B2 | Compositions and methods for increasing compliance with therapies using aldehyde dehydrogenase inhibitors and treating alcoholism | KRELE PHARMACEUTICALS, INC. (US) | 2012-01-10 | — | — | US | disclosed |
| EP-1441708-B1 | COMPOSITIONS AND METHODS FOR INCREASING COMPLIANCE WITH THERAPIES USING ALDEHYDE DEHYDROGENASE INHIBITORS AND TREATING ALCOHOLISM | KRELE PHARMACEUTICALS LLC (US) | 2009-04-08 | — | — | EP | disclosed |
| US-20090005441-A1 | COMPOSITIONS AND METHODS FOR INCREASING COMPLIANCE WITH THERAPIES USING ALDEHYDE DEHYDROGENASE INHIBITORS AND TREATING ALCOHOLISM | KRELE PHARMACEUTICALS, INC. (US) | 2009-01-01 | — | — | US | disclosed |
| EP-1441708-A4 | COMPOSITIONS AND METHODS FOR INCREASING COMPLIANCE WITH THERAPIES USING ALDEHYDE DEHYDROGENASE INHIBITORS AND TREATING ALCOHOLISM | KRELE PHARMACEUTICALS LLC (US) | 2007-05-23 | — | — | EP | disclosed |
| EP-1441708-A1 | COMPOSITIONS AND METHODS FOR INCREASING COMPLIANCE WITH THERAPIES USING ALDEHYDE DEHYDROGENASE INHIBITORS AND TREATING ALCOHOLISM | Krele Pharmaceuticals LLC (US) | 2004-08-04 | — | — | EP | disclosed |
| WO-2003039525-A1 | COMPOSITIONS AND METHODS FOR INCREASING COMPLIANCE WITH THERAPIES USING ALDEHYDE DEHYDROGENASE INHIBITORS AND TREATING ALCOHOLISM | KRELE PHARMACEUTICALS LLC (US) | 2003-05-15 | — | — | WO | disclosed |
| US-20030087814-A1 | Compositions and methods for increasing compliance with therapies using aldehyde dehydrogenase inhibitors and treating alcoholism | KRELE PHARMACEUTICALS, INC. | 2003-05-08 | — | — | US | disclosed |