Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH2 | P05091 | 20/20 | 1.00 |
| ▸ | MAOA | P21397 | 12/20 | 0.86 |
| ▸ | MAOB | P27338 | 12/20 | 0.86 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4686444 | 1.00 | ALDH2 (1.00) | ALDH2MAOAMAOB | |
| SCHEMBL4684115 | 1.00 | ALDH2 (1.00) | ALDH2MAOAMAOB | |
| SCHEMBL4684681 | 0.93 | ALDH2 (1.00) | ALDH2MAOAMAOB | |
| SCHEMBL5497011 | 0.91 | ALDH2 (1.00) | ALDH2MAOAMAOB | |
| SCHEMBL5492489 | 0.91 | ALDH2 (1.00) | ALDH2MAOAMAOB | |
| SCHEMBL1701152 | 0.91 | ALDH2 (1.00) | ALDH2MAOAMAOB | |
| SCHEMBL1701071 | 0.89 | ALDH2 (0.93) | ALDH2MAOAMAOB | |
| SCHEMBL7752699 | 0.89 | ALDH2 (1.00) | ALDH2MAOAMAOB | |
| SCHEMBL320049 | 0.89 | ALDH2 (1.00) | ALDH2MAOAMAOB | |
| SCHEMBL320544 | 0.89 | ALDH2 (1.00) | ALDH2MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1542675-A4 | COMPOUNDS USEFUL FOR THE INHIBITION OF ALDH | ENDOWMENT FOR RES IN HUMAN BIO (US) | 2008-11-19 | — | — | EP | disclosed |
| US-7368434-B2 | Compounds useful for the inhibition of ALDH | THE ENDOWMENT FOR RESEARCH IN HUMAN BIOLOGY, INC. (US) | 2008-05-06 | — | — | US | disclosed |
| EP-1542675-A1 | COMPOUNDS USEFUL FOR THE INHIBITION OF ALDH | The Endowment For Research In Human Biology, Inc. (US) | 2005-06-22 | — | — | EP | disclosed |
| US-20040068003-A1 | Compounds useful for the inhibition of ALDH | THE ENDOWMENT FOR RESEARCH IN HUMAN BIOLOGY, INC, | 2004-04-08 | — | — | US | disclosed |
| WO-2004002470-A1 | COMPOUNDS USEFUL FOR THE INHIBITION OF ALDH | THE ENDOWMENT FOR RESEARCH IN HUMAN BIOLOGY, INC. (US) | 2004-01-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040068003-A1 | Compounds useful for the inhibition of ALDH | ALDH2, ALDH1A1, ALDH3A1 | ALDH2 1/4885MAOA 484/4885MAOB 399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.