SCHEMBL3200465

SCHEMBL3200465

CCCCN=Cc1cc2ccccc2cc1C1=C(C)C(C)=CC1C

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
CA12 O43570 4/20 0.31
CA2 P00918 4/20 0.31
CA9 Q16790 4/20 0.31
EZH2 Q15910 1/20 0.31
OPRL1 P41146 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3201095 0.85 CA12 (0.37) KDM4EALDH1A1GAAMAPTCA12
SCHEMBL3201090 0.85 CA12 (0.37) KDM4EALDH1A1GAAMAPTCA12
SCHEMBL3201749 0.82 KDM4E (0.33) KDM4EALDH1A1GAAMAPTCA12
SCHEMBL3199818 0.80 GAA (0.36) KDM4EALDH1A1GAAMAPT
SCHEMBL3199814 0.80 GAA (0.36) KDM4EALDH1A1GAAMAPT
SCHEMBL3867658 0.78
SCHEMBL3213079 0.76 KDM4E (0.34) KDM4EALDH1A1GAAMAPTCA12
SCHEMBL3193632 0.75 KDM4E (0.33) KDM4EALDH1A1GAAMAPTCA12
SCHEMBL3215408 0.75 KDM4E (0.30) KDM4EALDH1A1GAAMAPT
SCHEMBL3199756 0.71 ALDH1A1 (0.34) KDM4EALDH1A1GAAMAPTCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7671226-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-02 US disclosed
EP-1426379-B1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME SUMITOMO CHEMICAL CO (JP) 2009-11-11 EP disclosed
US-7439379-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL CO., LTD. (JP) 2008-10-21 US disclosed
US-20040242410-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-02 US disclosed
EP-1426379-A1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME Sumitomo Chemical Company, Limited (JP) 2004-06-09 EP disclosed