Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 2/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 12/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3195664 | 0.93 | PSEN1 (0.44) | ACLYPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3201037 | 0.91 | ACLY (0.42) | ACLYPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3188777 | 0.88 | PSEN1 (0.42) | ACLYPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3201242 | 0.88 | PSEN1 (0.44) | ACLYPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3201811 | 0.87 | ACLY (0.38) | ACLYPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3190150 | 0.86 | PSEN1 (0.46) | ACLYPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3202361 | 0.86 | PSEN1 (0.44) | ACLYPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3190154 | 0.86 | PTPN1 (0.36) | ACLYPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3189150 | 0.85 | PTPN1 (0.36) | ACLYPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3192999 | 0.84 | PSEN1 (0.44) | ACLYPSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8206888-B2 | Radiation-sensitive resin composition | JSR CORPORATION (JP) | 2012-06-26 | — | — | US | disclosed |
| US-20100028800-A1 | RADIATION-SENSITIVE RESIN COMPOSITION | JSR CORPORATION (JP) | 2010-02-04 | — | — | US | disclosed |
| EP-1953593-A1 | RADIATION-SENSITIVE RESIN COMPOSITION | JSR Corporation (JP) | 2008-08-06 | — | — | EP | disclosed |
| US-6899989-B2 | Radiation-sensitive resin composition | JSR CORPORATION (JP) | 2005-05-31 | — | — | US | disclosed |