Acetic Acid

Acetic Acid

SCHEMBL320128

CC(=O)O.CCC(CC)C(N)(O)CC

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP1A2 P05177 1/20 0.33
THRB P10828 1/20 0.33
KMT2A Q03164 1/20 0.33
FFAR3 O14843 1/20 0.32
LCK P06239 1/20 0.32
FYN P06241 1/20 0.32
SLC1A3 P43003 1/20 0.30
SLC1A2 P43004 1/20 0.30
SLC1A1 P43005 1/20 0.30
KIF11 P52732 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2065877 0.88
Bromide SCHEMBL28516070 0.85
Iodide SCHEMBL28514467 0.85
Water SCHEMBL319960 0.85
Acetic Acid SCHEMBL25280990 0.81 MEN1 (0.35) MEN1ALDH1A1CYP1A2THRBKMT2A
Acetic Acid SCHEMBL2682620 0.77 MEN1 (0.33) MEN1ALDH1A1CYP1A2THRBKMT2A
Acetic Acid SCHEMBL1982442 0.77 MEN1 (0.33) MEN1ALDH1A1CYP1A2THRBKMT2A
SCHEMBL28322893 0.76
Acetic Acid SCHEMBL241364 0.75 FFAR3 (0.44) MEN1ALDH1A1CYP1A2THRBKMT2A
SCHEMBL9869570 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10717880-B2 Polyisocyanate-based anti-corrosion coating HUNTSMAN INTERNATIONAL LLC (US) 2020-07-21 US disclosed
US-10030094-B2 Polyisocyanurate-based syntactic coating for offshore applications HUNTSMAN INTERNATIONAL LLC (US) 2018-07-24 US disclosed
US-9926479-B2 Materials comprising a matrix and process for preparing them HUNTSMAN INTERNATIONAL LLC (US) 2018-03-27 US disclosed
US-9534072-B2 Polyisocyanate-based adhesive HUNTSMAN INTERNATIONAL LLC (US) 2017-01-03 US disclosed
EP-2300509-B1 A POLYISOCYANURATE-BASED SYNTACTIC COATING FOR OFFSHORE APPLICATIONS HUNTSMAN INT LLC (US) 2016-08-10 EP disclosed
EP-2245081-B1 ELASTOMERIC MATERIALS HAVING A HIGH HARDBLOCK CONTENT AND PROCESS FOR PREPARING THEM HUNTSMAN INT LLC (US) 2015-09-16 EP disclosed
US-20150125704-A1 Polyisocyanate-Based Anti-Corrosion Coating HUNTSMAN INTERNATIONAL LLC 2015-05-07 US disclosed
US-8962142-B2 Polyisocyanate-based anti-corrosion coating HUNTSMAN INTERNATIONAL LLC (US) 2015-02-24 US disclosed
US-8519062-B2 Elastomeric materials having a high hardblock content and process for preparing them HUNTSMAN INTERNATIONAL LLC (US) 2013-08-27 US disclosed
EP-2591029-A1 POLYISOCYANATE-BASED ANTI-CORROSION COATING Huntsman International LLC (US) 2013-05-15 EP disclosed
WO-2009101027-A1 ELASTOMERIC MATERIALS HAVING A HIGH HARDBLOCK CONTENT AND PROCESS FOR PREPARING THEM HUNTSMAN INTERNATIONAL LLC (US) 2009-08-20 WO disclosed
WO-2008110604-A1 POLYISOCYANATE-BASED ADHESIVE HUNTSMAN INTERNATIONAL LLC (US) 2008-09-18 WO disclosed
WO-2008110602-A1 POLYISOCYANATE-BASED ADHESIVE HUNTSMAN INTERNATIONAL LLC (US) 2008-09-18 WO disclosed
WO-2008110605-A1 POLYISOCYANATE-BASED ADHESIVE HUNTSMAN INTERNATIONAL LLC (US) 2008-09-18 WO disclosed
EP-1970420-A1 Polyisocyanate-based adhesive composition HUNTSMAN INTERNATIONAL LLC (US) 2008-09-17 EP disclosed
US-7405258-B2 Method for producing polyurethane emulsion for aqueous one-component coating agent NIPPON POLYURETHANE INDUSTRY CO., LTD. (JP) 2008-07-29 US disclosed
US-20070155894-A1 Method for producing polyurethane emulsion for aqueous one-component coating agent NIPPON POLYURETHANE INDUSTRY CO., LTD. 2007-07-05 US disclosed
EP-1721947-A1 PROCESS FOR PRODUCING POLYURETHANE EMULSION FOR WATER-BASED ONE-PACK TYPE COATING MATERIAL Nippon Polyurethane Industry Co., Ltd. (JP) 2006-11-15 EP disclosed
US-6596819-B2 An isocyanate group-terminated prepolymer having isocyanurate group and urethane group, obtained by reacting an organic polyisocyanate containing at least (a1) an aromatic diisocyanate with an active hydrogen group-containing compound NIPPON POLYURETHANE INDUSTRY CO., LTD. (JP) 2003-07-22 US disclosed
US-20030083451-A1 Polyisocyanate curing agent for laminate adhesive and process for production thereof NIPPON POLYURETHANE INDUSTRY CO., LTD. (JP) 2003-05-01 US disclosed