Water

Water

SCHEMBL319960

CCC(CC)C(N)(O)CC.O

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2065877 0.97
Bromide SCHEMBL28516070 0.94
Iodide SCHEMBL28514467 0.94
Acetic Acid SCHEMBL320128 0.85 MEN1 (0.33)
SCHEMBL28322893 0.84
SCHEMBL9869570 0.82
SCHEMBL7645790 0.79 FDPS (0.41)
SCHEMBL10644053 0.76 FDPS (0.36)
Hydrochloric Acid SCHEMBL28383617 0.74 FDPS (0.46)
Water SCHEMBL999492 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118125467-A Preparation method and application of Nb-Beta molecular sieve 中国科学院大连化学物理研究所 2024-06-04 CN claimed
CN-111825103-B Fluorine-containing high-silicon Y molecular sieve and preparation method thereof 中国科学院大连化学物理研究所 2022-04-12 CN claimed
CN-111825102-B Dry glue conversion synthesis method of high-silicon Y molecular sieve 中国科学院大连化学物理研究所 2022-03-22 CN claimed
CN-111825103-A Fluorine-containing high-silicon Y molecular sieve and preparation method thereof 中国科学院大连化学物理研究所 2020-10-27 CN claimed
CN-111825102-A Dry glue conversion synthesis method of high-silicon Y molecular sieve 中国科学院大连化学物理研究所 2020-10-27 CN claimed
CN-115772252-B TDI curing agent with low free monomer and good matte property, preparation method and application thereof 万华化学集团股份有限公司 2025-04-01 CN disclosed
CN-118125467-A Preparation method and application of Nb-Beta molecular sieve 中国科学院大连化学物理研究所 2024-06-04 CN disclosed
CN-112079979-B Bio-based pentamethylene diisocyanate curing agent and preparation method and application thereof 中海油常州涂料化工研究院有限公司 2022-08-09 CN disclosed
CN-111825103-B Fluorine-containing high-silicon Y molecular sieve and preparation method thereof 中国科学院大连化学物理研究所 2022-04-12 CN disclosed
CN-111825102-B Dry glue conversion synthesis method of high-silicon Y molecular sieve 中国科学院大连化学物理研究所 2022-03-22 CN disclosed
CN-112079979-A Bio-based pentamethylene diisocyanate curing agent and preparation method and application thereof 中海油常州涂料化工研究院有限公司 2020-12-15 CN disclosed
CN-111825102-A Dry glue conversion synthesis method of high-silicon Y molecular sieve 中国科学院大连化学物理研究所 2020-10-27 CN disclosed
WO-2008110604-A1 POLYISOCYANATE-BASED ADHESIVE HUNTSMAN INTERNATIONAL LLC (US) 2008-09-18 WO disclosed
WO-2008110602-A1 POLYISOCYANATE-BASED ADHESIVE HUNTSMAN INTERNATIONAL LLC (US) 2008-09-18 WO disclosed
EP-1970420-A1 Polyisocyanate-based adhesive composition HUNTSMAN INTERNATIONAL LLC (US) 2008-09-17 EP disclosed
US-7405258-B2 Method for producing polyurethane emulsion for aqueous one-component coating agent NIPPON POLYURETHANE INDUSTRY CO., LTD. (JP) 2008-07-29 US disclosed
US-20070155894-A1 Method for producing polyurethane emulsion for aqueous one-component coating agent NIPPON POLYURETHANE INDUSTRY CO., LTD. 2007-07-05 US disclosed
EP-1721947-A1 PROCESS FOR PRODUCING POLYURETHANE EMULSION FOR WATER-BASED ONE-PACK TYPE COATING MATERIAL Nippon Polyurethane Industry Co., Ltd. (JP) 2006-11-15 EP disclosed
US-6596819-B2 An isocyanate group-terminated prepolymer having isocyanurate group and urethane group, obtained by reacting an organic polyisocyanate containing at least (a1) an aromatic diisocyanate with an active hydrogen group-containing compound NIPPON POLYURETHANE INDUSTRY CO., LTD. (JP) 2003-07-22 US disclosed
US-20030083451-A1 Polyisocyanate curing agent for laminate adhesive and process for production thereof NIPPON POLYURETHANE INDUSTRY CO., LTD. (JP) 2003-05-01 US disclosed