SCHEMBL3201455

SCHEMBL3201455

Cc1ccccc1NN=Cc1ccccc1C1C=Cc2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 13/20 0.41
MEN1 O00255 8/20 0.41
KMT2A Q03164 8/20 0.41
KDM4E B2RXH2 7/20 0.41
GAA P10253 6/20 0.41
ALDH1A1 P00352 6/20 0.41
LMNA P02545 5/20 0.41
TDP1 Q9NUW8 4/20 0.41
NPC1 O15118 12/20 0.38
RAB9A P51151 10/20 0.38
HPGD P15428 3/20 0.38
POLB P06746 2/20 0.35
PLA2G1B P04054 1/20 0.35
XBP1 P17861 1/20 0.35
HTT P42858 1/20 0.35
RECQL P46063 1/20 0.35
MCL1 Q07820 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
ATG4B Q9Y4P1 1/20 0.35
CYP1A2 P05177 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3201446 1.00 MAPT (0.41) MAPTMEN1KMT2AKDM4EGAA
SCHEMBL3215907 0.82 MEN1 (0.40) MAPTMEN1KMT2AKDM4EGAA
SCHEMBL3199582 0.82 MAPT (0.34) MAPTMEN1KMT2AKDM4EGAA
SCHEMBL3199585 0.82 MAPT (0.34) MAPTMEN1KMT2AKDM4EGAA
SCHEMBL3210132 0.81 MAPT (0.49) MAPTMEN1KMT2AKDM4EGAA
SCHEMBL3210138 0.81 MAPT (0.49) MAPTMEN1KMT2AKDM4EGAA
SCHEMBL3202364 0.77 LMNA (0.35) KDM4EGAAALDH1A1LMNAPOLB
SCHEMBL3202356 0.77 LMNA (0.35) KDM4EGAAALDH1A1LMNAPOLB
SCHEMBL3216662 0.77 MAPT (0.41) MAPTMEN1KMT2AKDM4EGAA
SCHEMBL3216654 0.77 MAPT (0.41) MAPTMEN1KMT2AKDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7732643-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-08 US disclosed
US-7671226-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-02 US disclosed
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME HANAOKA HIDENORI 2010-02-25 US disclosed
EP-1426379-B1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME SUMITOMO CHEMICAL CO (JP) 2009-11-11 EP disclosed
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same HANAOKA HIDENORI 2009-02-26 US disclosed
US-7439379-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL CO., LTD. (JP) 2008-10-21 US disclosed
US-20040242410-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-02 US disclosed
EP-1426379-A1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME Sumitomo Chemical Company, Limited (JP) 2004-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same C1R, C1S, AP1M1 MAPT 2641/4885MEN1 1101/4885KMT2A 2101/4885
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME C1R, C1S, AP1M1 MAPT 2641/4885MEN1 1101/4885KMT2A 2101/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.