SCHEMBL3201718

SCHEMBL3201718

Cc1cc(C)c(N=Cc2c(C3C=Cc4ccccc43)ccc3ccccc23)c(C)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 10/20 0.37
MAPT P10636 9/20 0.37
MEN1 O00255 8/20 0.37
GAA P10253 5/20 0.37
HCRTR1 O43613 1/20 0.37
CASP1 P29466 1/20 0.37
CASP7 P55210 1/20 0.37
ALDH1A1 P00352 5/20 0.35
HTT P42858 3/20 0.35
LMNA P02545 3/20 0.35
NPSR1 Q6W5P4 1/20 0.34
POLB P06746 2/20 0.34
RRM1 P23921 1/20 0.34
THRB P10828 3/20 0.33
KDM4E B2RXH2 3/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
BLM P54132 1/20 0.33
CASP6 P55212 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CYP1A2 P05177 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3201710 1.00 KMT2A (0.37) KMT2AMAPTMEN1GAAHCRTR1
SCHEMBL3199598 0.83 KMT2A (0.51) KMT2AMAPTMEN1GAAALDH1A1
SCHEMBL3199608 0.83 KMT2A (0.51) KMT2AMAPTMEN1GAAALDH1A1
SCHEMBL3200783 0.80 MAPT (0.37) KMT2AMAPTMEN1GAAHCRTR1
SCHEMBL3200786 0.80 MAPT (0.37) KMT2AMAPTMEN1GAAHCRTR1
SCHEMBL3201658 0.80 ALDH1A1 (0.32) MAPTGAAALDH1A1LMNAPOLB
SCHEMBL3201667 0.80 ALDH1A1 (0.32) MAPTGAAALDH1A1LMNAPOLB
SCHEMBL3201741 0.78 MAPT (0.36) KMT2AMAPTMEN1GAAHCRTR1
SCHEMBL3201731 0.78 MAPT (0.36) KMT2AMAPTMEN1GAAHCRTR1
SCHEMBL3207647 0.77 KMT2A (0.35) KMT2AMAPTMEN1GAAHCRTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7732643-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-08 US disclosed
US-7671226-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-02 US disclosed
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME HANAOKA HIDENORI 2010-02-25 US disclosed
EP-1426379-B1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME SUMITOMO CHEMICAL CO (JP) 2009-11-11 EP disclosed
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same HANAOKA HIDENORI 2009-02-26 US disclosed
US-7439379-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL CO., LTD. (JP) 2008-10-21 US disclosed
US-20040242410-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-02 US disclosed
EP-1426379-A1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME Sumitomo Chemical Company, Limited (JP) 2004-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same C1R, C1S, AP1M1 KMT2A 2101/4885MAPT 2641/4885MEN1 1101/4885
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME C1R, C1S, AP1M1 KMT2A 2101/4885MAPT 2641/4885MEN1 1101/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.