SCHEMBL3202824

SCHEMBL3202824

Cc1cc(C)c(NC(C)(C)c2ccccc2C2c3ccccc3-c3ccccc32)c(C)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.35
KMT2A Q03164 6/20 0.35
POLB P06746 3/20 0.35
MAPT P10636 3/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
NSD2 O96028 2/20 0.35
ALDH1A1 P00352 2/20 0.35
THRB P10828 2/20 0.35
HPGD P15428 2/20 0.35
MAPK1 P28482 2/20 0.35
RECQL P46063 2/20 0.35
P2RY1 P47900 2/20 0.35
NPSR1 Q6W5P4 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
TP53 P04637 1/20 0.35
RAPGEF4 Q8WZA2 8/20 0.33
FFAR4 Q5NUL3 1/20 0.33
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3205111 0.81 TACR1 (0.33) TP53RAPGEF4FFAR4
SCHEMBL3203280 0.77 TACR1 (0.31) TP53FFAR4
SCHEMBL3213298 0.77 NPSR1 (0.35) MEN1KMT2APOLBMAPTSMN1; SMN2
SCHEMBL3209488 0.76 TP53 (0.32) TP53RAPGEF4FFAR4
SCHEMBL3205293 0.73 GPR3 (0.34) MEN1KMT2APOLB
SCHEMBL3868150 0.73 MEN1 (0.33) MEN1KMT2A
SCHEMBL3206060 0.73 POLB (0.33) MEN1KMT2APOLBMAPTSMN1; SMN2
Hydrochloric Acid SCHEMBL3258788 0.72 GPR3 (0.30)
SCHEMBL3200331 0.72 MEN1 (0.32) MEN1KMT2APOLBMAPTSMN1; SMN2
SCHEMBL3199077 0.71 TP53 (0.37) MEN1KMT2APOLBMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7671226-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-02 US disclosed
EP-1426379-B1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME SUMITOMO CHEMICAL CO (JP) 2009-11-11 EP disclosed
US-7439379-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL CO., LTD. (JP) 2008-10-21 US disclosed