Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | TSPO | P30536 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | RGS4 | P49798 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3210071 | 0.88 | MEN1 (0.54) | MEN1KMT2AP2RX4GAAMAPK1 | |
| SCHEMBL3220778 | 0.77 | MEN1 (0.43) | MEN1KMT2AP2RX4GAAMAPK1 | |
| SCHEMBL3207858 | 0.77 | ALDH1A1 (0.52) | MEN1KMT2AGAAKDM4EL3MBTL1 | |
| SCHEMBL3221008 | 0.73 | MEN1 (0.50) | MEN1KMT2AP2RX4GAAMAPK1 | |
| SCHEMBL3210120 | 0.73 | KDM4E (0.49) | MEN1KMT2AP2RX4GAASMN1; SMN2 | |
| SCHEMBL11257792 | 0.67 | MEN1 (0.64) | MEN1KMT2AP2RX4GAAMAPK1 | |
| SCHEMBL3208581 | 0.66 | ALDH1A1 (0.46) | MEN1KMT2AP2RX4GAAMAPK1 | |
| SCHEMBL3927424 | 0.64 | CNR2 (0.66) | MEN1KMT2AP2RX4GAASMN1; SMN2 | |
| SCHEMBL11263773 | 0.64 | MEN1 (0.72) | MEN1KMT2AP2RX4GAAMAPK1 | |
| Trifluoroacetic Acid SCHEMBL31197678 | 0.63 | MEN1 (0.58) | MEN1KMT2AP2RX4GAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056515-A1 | BENZIMIDAZOLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056515-A1 | BENZIMIDAZOLE COMPOUNDS | HRH4, SSTR5, CNR1 | MEN1 1490/4885KMT2A 2341/4885P2RX4 365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.