Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | LAP3 | P28838 | 3/20 | 0.41 |
| ▸ | ANPEP | P15144 | 2/20 | 0.41 |
| ▸ | SMPD2 | O60906 | 1/20 | 0.40 |
| ▸ | ACP3 | P15309 | 2/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.38 |
| ▸ | EPOR | P19235 | 1/20 | 0.38 |
| ▸ | CPA1 | P15085 | 2/20 | 0.37 |
| ▸ | CPA3 | P15088 | 2/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | CPB1 | P15086 | 1/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3209764 | 0.89 | SLC7A5 (0.42) | LAP3ANPEPSMPD2SLC7A5ERAP2 | |
| SCHEMBL2991862 | 0.77 | LAP3 (0.50) | CYP1A2LAP3ANPEPACP3ALPI | |
| SCHEMBL2991859 | 0.77 | LAP3 (0.50) | CYP1A2LAP3ANPEPACP3ALPI | |
| SCHEMBL2296250 | 0.77 | CYP1A2 (0.47) | CYP1A2ALPIPKMPTGS1XIAP | |
| SCHEMBL2296245 | 0.77 | CYP1A2 (0.47) | CYP1A2ALPIPKMPTGS1XIAP | |
| SCHEMBL3217791 | 0.77 | SMPD2 (0.43) | SMPD2 | |
| SCHEMBL3190718 | 0.77 | SRC (0.37) | SMPD2ACP3 | |
| SCHEMBL3226044 | 0.75 | SMPD2 (0.31) | SMPD2 | |
| SCHEMBL3195177 | 0.75 | EPOR (0.42) | SMPD2EPORFOLH1 | |
| SCHEMBL8610496 | 0.75 | ALPI (0.46) | CYP1A2ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | disclosed |
| US-7776844-B2 | N-(phosphonoalkyl)-amino acids, derivatives thereof and compositions and methods of use | YU RUEY J | 2010-08-17 | — | — | US | disclosed |
| US-20090208499-A1 | N-(Phosphonoalkyl)-Amino Acids, Derivatives Thereof and Compositions and Methods of Use | YU RUEY J | 2009-08-20 | — | — | US | disclosed |
| US-7572776-B2 | N-(phosphonoalkyl)-amino acids, derivatives thereof and compositions and methods of use | YU RUEY J | 2009-08-11 | — | — | US | disclosed |
| US-20080306025-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2008-12-11 | — | — | US | disclosed |
| EP-1979366-A2 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | Yu, Ruey J. (US) | 2008-10-15 | — | — | EP | disclosed |
| US-7429575-B2 | N-(phosphonoalkyl)-amino acids, derivatives thereof and compositions and methods of use | YU RUEY J | 2008-09-30 | — | — | US | disclosed |
| WO-2007082206-A2 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J (US) | 2007-07-19 | — | — | WO | disclosed |
| US-20070161543-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2007-07-12 | — | — | US | disclosed |