SCHEMBL3202959

SCHEMBL3202959

CCOP(=O)(CCCn1c2ccc(C(C)(C)C)cc2c2cc(C(C)(C)C)ccc21)OCC

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RORA P35398 6/20 0.50
RORC P51449 6/20 0.50
RORB Q92753 6/20 0.50
PGR P06401 6/20 0.50
PSEN1 P49768 1/20 0.46
PSEN2 P49810 1/20 0.46
APH1B Q8WW43 1/20 0.46
NCSTN Q92542 1/20 0.46
APH1A Q96BI3 1/20 0.46
PSENEN Q9NZ42 1/20 0.46
HTR1D P28221 1/20 0.36
PLK1 P53350 1/20 0.36
DNMT1 P26358 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31609237 0.84 RORA (0.48) RORARORCRORBPGRPSEN1
SCHEMBL31219160 0.83 PSEN1 (0.47) RORARORCRORBPSEN1PSEN2
SCHEMBL31250783 0.82 PSEN1 (0.48) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL3214427 0.81 RORA (0.51) RORARORCRORBPGRHTR1D
SCHEMBL31240191 0.81 RORA (0.51) RORARORCRORBPGRHTR1D
SCHEMBL31609280 0.80 PSEN1 (0.49) RORARORCRORBPGRPSEN1
Butane SCHEMBL3202948 0.80 RORA (0.54) RORARORCRORBPGRHTR1D
SCHEMBL30972550 0.80 PSEN1 (0.49) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL31609243 0.80 PSEN1 (0.52) RORARORCRORBPGRPSEN1
SCHEMBL3217390 0.79 PSEN1 (0.62) RORARORCRORBPGRPSEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8405069-B2 Printable thin-film transistors with high dielectric constant gate insulators and methods for producing same GEORGIA TECH RESEARCH CORPORATION (US) 2013-03-26 US disclosed
US-8405069-B2 Printable thin-film transistors with high dielectric constant gate insulators and methods for producing same GEORGIA TECH RESEARCH CORPORATION (US) 2013-03-26 US disclosed
US-8405069-B2 Printable thin-film transistors with high dielectric constant gate insulators and methods for producing same GEORGIA TECH RESEARCH CORPORATION (US) 2013-03-26 US disclosed
US-20100051917-A1 PRINTABLE THIN-FILM TRANSISTORS WITH HIGH DIELECTRIC CONSTANT GATE INSULATORS AND METHODS FOR PRODUCING SAME NATIONAL SCIENCE FOUNDATION 2010-03-04 US disclosed
US-20100051917-A1 PRINTABLE THIN-FILM TRANSISTORS WITH HIGH DIELECTRIC CONSTANT GATE INSULATORS AND METHODS FOR PRODUCING SAME NATIONAL SCIENCE FOUNDATION 2010-03-04 US disclosed
US-20100051917-A1 PRINTABLE THIN-FILM TRANSISTORS WITH HIGH DIELECTRIC CONSTANT GATE INSULATORS AND METHODS FOR PRODUCING SAME NATIONAL SCIENCE FOUNDATION 2010-03-04 US disclosed
US-20100027192-A1 COATED METAL OXIDE NANOPARTICLES AND METHODS FOR PRODUCING SAME GEORGIA TECH RESEARCH CORPORATION 2010-02-04 US disclosed
US-20100027192-A1 COATED METAL OXIDE NANOPARTICLES AND METHODS FOR PRODUCING SAME GEORGIA TECH RESEARCH CORPORATION 2010-02-04 US disclosed
US-20100027192-A1 COATED METAL OXIDE NANOPARTICLES AND METHODS FOR PRODUCING SAME GEORGIA TECH RESEARCH CORPORATION 2010-02-04 US disclosed
WO-2008060534-A1 PRINTABLE THIN-FILM TRANSISTORS WITH HIGH DIELECTRIC CONSTANT GATE INSULATORS AND METHODS FOR PRODUCING SAME GEORGIA TECH RESEARCH CORPORATION (US) 2008-05-22 WO disclosed
EP-1888311-A2 COATED METAL OXIDE NANOPARTICLES AND METHODS FOR PRODUCING SAME GEORGIA TECH RESEARCH CORPORATION (US) 2008-02-20 EP disclosed
WO-2006124670-A2 COATED METAL OXIDE NANOPARTICLES AND METHODS FOR PRODUCING SAME GEORGIA TECH RESEARCH CORPORATION (US) 2006-11-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100027192-A1 COATED METAL OXIDE NANOPARTICLES AND METHODS FOR PRODUCING SAME NCL, PNN, NCDN RORA 1730/4885RORC 1586/4885RORB 2220/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.