SCHEMBL3202964

SCHEMBL3202964

c1ccc(NN=C(CC2c3ccccc3-c3ccccc32)c2ccccc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.47
MAPT P10636 9/20 0.47
GAA P10253 8/20 0.47
KMT2A Q03164 7/20 0.47
MEN1 O00255 6/20 0.47
KDM4E B2RXH2 4/20 0.47
TDP1 Q9NUW8 4/20 0.47
TAAR1 Q96RJ0 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.45
NPC1 O15118 2/20 0.45
HPGD P15428 2/20 0.45
HTT P42858 2/20 0.41
CA1 P00915 3/20 0.40
CA2 P00918 3/20 0.40
LMNA P02545 2/20 0.39
CA4 P22748 2/20 0.39
CA9 Q16790 2/20 0.39
MAPK1 P28482 2/20 0.38
RAB9A P51151 2/20 0.38
THRB P10828 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3199330 0.85 CA1 (0.39) ALDH1A1MAPTGAAKMT2AMEN1
SCHEMBL3214259 0.83 HPGD (0.41) ALDH1A1MAPTGAATDP1SMN1; SMN2
SCHEMBL3210970 0.82 HTR2A (0.35) ALDH1A1MAPTGAAKMT2AMEN1
SCHEMBL3192712 0.82 MAPT (0.39) ALDH1A1MAPTGAAKMT2AMEN1
SCHEMBL3199326 0.80 KMT2A (0.42) KMT2AMEN1KDM4ESMN1; SMN2HPGD
SCHEMBL3206071 0.78 CA1 (0.40) ALDH1A1MAPTGAAKMT2AMEN1
SCHEMBL3202181 0.77 ALDH1A1 (0.38) ALDH1A1MAPTGAAKMT2AMEN1
SCHEMBL3207540 0.76 BCHE (0.43) ALDH1A1KMT2AMEN1SMN1; SMN2NPC1
SCHEMBL3276647 0.75 GAA (0.59) ALDH1A1MAPTGAAKMT2AMEN1
SCHEMBL2681227 0.75 GAA (0.59) ALDH1A1MAPTGAAKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7671226-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-02 US disclosed
EP-1426379-B1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME SUMITOMO CHEMICAL CO (JP) 2009-11-11 EP disclosed
US-7439379-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL CO., LTD. (JP) 2008-10-21 US disclosed