SCHEMBL3203187

SCHEMBL3203187

C=CC(=O)OCCN(CO)CO

nearest known ligand 0.59

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.59
ALDH1A1 P00352 5/20 0.54
TP53 P04637 3/20 0.54
HIF1A Q16665 3/20 0.54
CYP3A4 P08684 2/20 0.54
HSD17B10 Q99714 2/20 0.54
HPGD P15428 2/20 0.48
SMN1; SMN2 Q16637 3/20 0.44
MAPK1 P28482 1/20 0.44
THRB P10828 2/20 0.41
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
POLB P06746 1/20 0.31
KDM4E B2RXH2 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22063816 0.92 TSHR (0.55) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL16294460 0.90 TSHR (0.59) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL7050406 0.89 TSHR (0.60) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL10781384 0.87 TSHR (0.58) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL16295834 0.86 TSHR (0.64) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL22465822 0.86 TSHR (0.63) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL4399489 0.86 TSHR (0.63) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL769713 0.84 TSHR (0.61) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL4387485 0.83 TSHR (0.46) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL10698787 0.82 TSHR (0.57) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3030592-A1 HYDROPHILIC COATINGS FORMED BY ATMOSPHERIC CO2 REACTION Empire Technology Development LLC (US) 2016-06-15 EP disclosed
US-20160145456-A1 HYDROPHILIC COATINGS FORMED BY ATMOSPHERIC CO2 REACTION CRESTLINE DIRECT FINANCE, L.P. 2016-05-26 US disclosed
WO-2014200484-A1 HYDROPHILIC COATINGS FORMED BY ATMOSPHERIC CO2 REACTION EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2014-12-18 WO disclosed
US-8399061-B2 Anti-corrosion agent forming a coating film with good adhesion and method for nongalvanic application thereof BASF COATINGS GMBH (DE) 2013-03-19 US disclosed
US-20100098842-A1 PROCESS FOR CORROSION-PROOFING METALLIC SUBSTRATES BASF COATINGS AG (DE) 2010-04-22 US disclosed
US-20100040798-A1 COAT-FORMING CORROSION PREVENTATIVE WITH GOOD ADHESION AND PROCESS FOR ITS ELECTROLESS APPLICATION BASF COATINGS AG (DE) 2010-02-18 US disclosed
US-20080255308-A1 Powder Slurries Which can be Thermally Hardened with Actinic Radiation and Method for the Production and Use Thereof BASF COATINGS AG (DE) 2008-10-16 US disclosed
US-7297723-B2 Powder slurries which can be hardened thermally and by means of actinic radiation, a method for the production thereof and the use of the same BASF COATINGS AG (DE) 2007-11-20 US disclosed
US-7151130-B2 Polyurethane-modified copolymers, method for their production and the use thereof BASF COATINGS AG (DE) 2006-12-19 US disclosed
US-7122289-B2 Mixture which can be thermally hardened and hardened by actinic radiation and use thereof BASF COATINGS AG (DE) 2006-10-17 US disclosed
US-7022748-B2 Aqueous dispersions, which can be hardened thermally and by using actinic radiation, method for the production thereof and their use BASF COATINGS AG (DE) 2006-04-04 US disclosed
US-6916878-B2 Aqueous dispersions that are free or substantially free from volatile organic compounds, and method for their production and use thereof BASF COATINGS AG (DE) 2005-07-12 US disclosed
US-20040059053-A1 Aqueous dispersions that are free or substantially free from volatile organic compounds, and method for their production and use thereof BASF COATINGS AKTIENGESELLSCHAFT (DE) 2004-03-25 US disclosed
US-20040053159-A1 Mixture which can be thermally hardened and hardened by actinic radiation and use thereof BASF COATINGS AKTIENGESELSCHAFT (DE) 2004-03-18 US disclosed
US-20040052966-A1 Aqueous dispersions, which can be hardened thermally and by using actinic radiation, method for the production thereof and their use BASF COATING AKTIENGESELLSCHAFT (DE) 2004-03-18 US disclosed
US-20040048977-A1 Powder slurries which can be hardened thermally and by means of actinic radiation, a method for the production thereof and the use of the same BASF COATING AKTIENGESELLSCHAFT (DE) 2004-03-11 US disclosed
US-20040048976-A1 Polyurethane-modified copolymers, method for their production and the use thereof BASF COATINGS AKTIENGESELLSCHAFT (DE) 2004-03-11 US disclosed