Known targets — ChEMBL curated mechanism
CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8
The experimentally established mechanism targets of Phloroglucinol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL320498 | 0.91 | — | — | |
| Resorcinol SCHEMBL320303 | 0.88 | CA12 (0.44) | — | |
| SCHEMBL14301560 | 0.68 | — | — | |
| SCHEMBL22719764 | 0.67 | — | — | |
| SCHEMBL13993013 | 0.65 | ESR1 (0.37) | — | |
| SCHEMBL18402718 | 0.65 | — | — | |
| SCHEMBL14099357 | 0.65 | — | — | |
| SCHEMBL17827206 | 0.64 | — | — | |
| SCHEMBL14730569 | 0.62 | ALDH1A1 (0.36) | — | |
| SCHEMBL19129077 | 0.61 | APP (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012006245-A1 | PHLOROGLUCINOL REDUCTASE AND METHODS OF MAKING AND USING THE SAME | DRATHS CORPORATION (US) | 2012-01-12 | — | — | WO | disclosed |