SCHEMBL3203478

SCHEMBL3203478

CC1=CC(C)=C(c2ccccc2C=NNc2c(C)cc(C)cc2C)C1C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.36
RAB9A P51151 6/20 0.36
NPC1 O15118 4/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
LMNA P02545 8/20 0.34
KMT2A Q03164 6/20 0.34
MEN1 O00255 4/20 0.34
ALDH1A1 P00352 2/20 0.34
POLB P06746 2/20 0.34
HPGD P15428 1/20 0.34
HTT P42858 5/20 0.33
KDM4E B2RXH2 4/20 0.33
GAA P10253 4/20 0.33
MAPK1 P28482 1/20 0.32
PLA2G1B P04054 2/20 0.31
ATG4B Q9Y4P1 2/20 0.31
NPSR1 Q6W5P4 2/20 0.31
XBP1 P17861 1/20 0.31
RECQL P46063 1/20 0.31
MCL1 Q07820 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3203470 1.00 MAPT (0.36) MAPTRAB9ANPC1SMN1; SMN2LMNA
SCHEMBL3192758 0.83 MAPT (0.40) MAPTRAB9ANPC1SMN1; SMN2LMNA
SCHEMBL3192760 0.83 MAPT (0.40) MAPTRAB9ANPC1SMN1; SMN2LMNA
SCHEMBL3203093 0.83 MAPT (0.46) MAPTRAB9ANPC1SMN1; SMN2LMNA
SCHEMBL3203096 0.83 MAPT (0.46) MAPTRAB9ANPC1SMN1; SMN2LMNA
SCHEMBL3214574 0.82 LMNA (0.35) MAPTRAB9ANPC1SMN1; SMN2LMNA
SCHEMBL3214581 0.82 LMNA (0.35) MAPTRAB9ANPC1SMN1; SMN2LMNA
SCHEMBL3202311 0.81 MAPT (0.32) MAPTRAB9ANPC1SMN1; SMN2LMNA
SCHEMBL3215483 0.79 KMT2A (0.46) MAPTRAB9ANPC1SMN1; SMN2LMNA
SCHEMBL3215474 0.79 KMT2A (0.46) MAPTRAB9ANPC1SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7732643-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-08 US disclosed
US-7671226-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-02 US disclosed
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME HANAOKA HIDENORI 2010-02-25 US disclosed
EP-1426379-B1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME SUMITOMO CHEMICAL CO (JP) 2009-11-11 EP disclosed
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same HANAOKA HIDENORI 2009-02-26 US disclosed
US-7439379-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL CO., LTD. (JP) 2008-10-21 US disclosed
US-20040242410-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-02 US disclosed
EP-1426379-A1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME Sumitomo Chemical Company, Limited (JP) 2004-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same C1R, C1S, AP1M1 MAPT 2641/4885RAB9A 1759/4885NPC1 2173/4885
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME C1R, C1S, AP1M1 MAPT 2641/4885RAB9A 1759/4885NPC1 2173/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.