Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL118850 | 0.82 | — | — | |
| Bromide SCHEMBL3725335 | 0.82 | — | — | |
| Bromide SCHEMBL449 | 0.82 | — | — | |
| Bromide SCHEMBL360044 | 0.82 | — | — | |
| Bromide SCHEMBL3378419 | 0.67 | — | — | |
| Bromide SCHEMBL5672745 | 0.67 | — | — | |
| Bromide SCHEMBL11786078 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL4185254 | 0.67 | — | — | |
| SCHEMBL1505844 | 0.67 | — | — | |
| Bromide SCHEMBL8112164 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109232887-A | A kind of shape-memory polymer and preparation method thereof that crosslinking points are controllable | 中国科学院成都有机化学有限公司 | 2019-01-18 | — | — | CN | claimed |
| CN-109232887-A | A kind of shape-memory polymer and preparation method thereof that crosslinking points are controllable | 中国科学院成都有机化学有限公司 | 2019-01-18 | — | — | CN | disclosed |
| US-7678869-B2 | Atom or group transfer radical polymerization | CARNEGIE MELLON UNIVERSITY (US) | 2010-03-16 | — | — | US | disclosed |
| US-20060258826-A1 | Atom or group transfer radical polymerization | CARNEGIE MELLON UNIVERSITY | 2006-11-16 | — | — | US | disclosed |
| EP-0966489-B1 | IMPROVEMENTS IN ATOM OR GROUP TRANSFER RADICAL POLYMERIZATION | UNIV CARNEGIE MELLON (US) | 2006-11-15 | — | — | EP | disclosed |
| US-7125938-B2 | Atom or group transfer radical polymerization | CARNEGIE MELLON UNIVERSITY (US) | 2006-10-24 | — | — | US | disclosed |
| US-20040204556-A1 | Atom or group transfer radical polymerization | MATYJASZEWSKI KRZYSZTOF (US) | 2004-10-14 | — | — | US | disclosed |
| US-6541580-B1 | Controlling living polymerization via e.g. polyphosphazene initiators | CARNEGIE MELLON UNIVERSITY | 2003-04-01 | — | — | US | disclosed |
| US-6512060-B1 | Contacting at least one first molecule comprising one or more radically transferable atoms or groups, and at least one second molecule comprising one or more radically transferable atoms or groups with a system comprising: a transition metal, | CARNEGIE MELLON UNIVERSITY | 2003-01-28 | — | — | US | disclosed |
| US-5214044-A | Antiallergens | PFIZER INC. (US) | 1993-05-25 | — | — | US | disclosed |
| US-5120747-A | Antiallergens, antiinflammatory agent | PFIZER INC. (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0470078-A1 | 1,4-DIHYDROPYRIDINES | Pfizer Limited (GB) | 1992-02-12 | — | — | EP | disclosed |
| US-5070205-A | Chemical intermediate for anticoagulants | PFIZER INC. (US) | 1991-12-03 | — | — | US | disclosed |
| EP-0310386-B1 | 4-ARYL-5-CARBAMOYL-1,4-DIHYDROPYRIDINES | Pfizer Limited (GB) | 1991-11-06 | — | — | EP | disclosed |
| US-5063237-A | Antiallergens and antiinflammatory agents | PFIZER INC. (US) | 1991-11-05 | — | — | US | disclosed |
| US-4963560-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | PFIZER INC. (US) | 1990-10-16 | — | — | US | disclosed |
| WO-1990011280-A1 | 1,4-DIHYDROPYRIDINES | PFIZER LIMITED (GB) | 1990-10-04 | — | — | WO | disclosed |
| US-4935430-A | Platelet activating factor antagonists | PFIZER INC. (US) | 1990-06-19 | — | — | US | disclosed |
| EP-0365140-A1 | 1,4-Dihydropyridine derivatives | Pfizer Limited (GB) | 1990-04-25 | — | — | EP | disclosed |
| EP-0310386-A2 | 4-Aryl-5-carbamoyl-1,4-dihydropyridines | Pfizer Limited (GB) | 1989-04-05 | — | — | EP | disclosed |