Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL449 | 0.82 | — | — | |
| Bromide SCHEMBL3725335 | 0.82 | — | — | |
| Bromide SCHEMBL118850 | 0.82 | — | — | |
| Bromide SCHEMBL5341109 | 0.67 | CA1 (0.33) | — | |
| Bromide SCHEMBL11589597 | 0.67 | CA1 (0.33) | — | |
| Bromide SCHEMBL11786078 | 0.67 | — | — | |
| Bromide SCHEMBL6946786 | 0.67 | — | — | |
| Bromide SCHEMBL11339883 | 0.67 | — | — | |
| Bromide SCHEMBL7759692 | 0.67 | CA1 (0.33) | — | |
| Bromide SCHEMBL11006972 | 0.67 | CA4 (0.67) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109082280-B | Preparation method of liquid crystal material | 宁夏中星显示材料有限公司 | 2020-07-28 | — | — | CN | claimed |
| CN-109082280-A | A kind of preparation method of liquid crystal material | 宁夏中星显示材料有限公司 | 2018-12-25 | — | — | CN | claimed |
| CN-105037199-A | Bromoazobenzene compound and preparation method thereof | UNIV LINGNAN NORMAL | 2015-11-11 | — | — | CN | claimed |
| CN-1181036-C | 2,3,5-tribromobenzoic acid as plant growth regulator and its preparing process | 汪敬恒 | 2004-12-22 | — | — | CN | claimed |
| CN-1369474-A | 2,3,5-tribromobenzoic acid as plant growth regulator and its preparing process | WANG JINGHENG (CN) | 2002-09-18 | — | — | CN | claimed |
| CN-117247340-A | Preparation method of 1-nitro-2-halogen-4-methylthiobenzene | 韶远科技（上海)有限公司 | 2023-12-19 | — | — | CN | disclosed |
| CN-109082280-B | Preparation method of liquid crystal material | 宁夏中星显示材料有限公司 | 2020-07-28 | — | — | CN | disclosed |
| CN-109082280-A | A kind of preparation method of liquid crystal material | 宁夏中星显示材料有限公司 | 2018-12-25 | — | — | CN | disclosed |
| CN-105037199-A | Bromoazobenzene compound and preparation method thereof | UNIV LINGNAN NORMAL | 2015-11-11 | — | — | CN | disclosed |
| CN-101948372-B | 2-methoxyl-3,4-difluorobenzene, preparation method and application thereof | UNIV TSINGHUA | 2012-07-04 | — | — | CN | disclosed |
| CN-101747309-B | Lateral difluoro methylene ether bridged bond fluoroalkyl terphenyl liquid crystal compound and preparation method and application thereof | UNIV TSINGHUA | 2012-05-23 | — | — | CN | disclosed |
| CN-101948372-A | 2-methoxyl-3,4-difluorobenzene, preparation method and application thereof | UNIV TSINGHUA | 2011-01-19 | — | — | CN | disclosed |
| CN-101747309-A | Fluoro-alkyl terphenyl liquid crystal compound with sidewise difluoro methylene ether bridged bond as well as preparation method and application thereof | UNIV TSINGHUA | 2010-06-23 | — | — | CN | disclosed |
| US-7709542-B2 | Proton-exchange composite containing nanoparticles having outer oligomeric ionomer, and methods of forming | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2010-05-04 | — | — | US | disclosed |
| US-20080233451-A1 | Proton-exchange composite containing nanoparticles having outer oligomeric ionomer, and methods of forming | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2008-09-25 | — | — | US | disclosed |
| CN-1181036-C | 2,3,5-tribromobenzoic acid as plant growth regulator and its preparing process | 汪敬恒 | 2004-12-22 | — | — | CN | disclosed |
| EP-0411150-B1 | INDOLE DERIVATIVES, PREPARATION THEREOF, AND DRUG FOR PREVENTING AND TREATING NEPHRITIS CONTAINING SAME | OTSUKA PHARMA CO LTD (JP) | 1996-11-27 | — | — | EP | disclosed |
| US-5238938-A | Nephrosis | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-24 | — | — | US | disclosed |
| EP-0411150-A1 | INDOLE DERIVATIVES, PREPARATION THEREOF, AND DRUG FOR PREVENTING AND TREATING NEPHRITIS CONTAINING SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-06 | — | — | EP | disclosed |