SCHEMBL320387

SCHEMBL320387

CCO[Si](Cc1ccc(Cl)cc1)(OCC)OCC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.41
IDO1 P14902 3/20 0.39
AGXT P21549 2/20 0.39
KDM4E B2RXH2 2/20 0.39
THRB P10828 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
SLC6A2 P23975 2/20 0.36
SLC6A3 Q01959 2/20 0.36
HTR2A P28223 1/20 0.36
SLC6A4 P31645 1/20 0.36
HRH1 P35367 1/20 0.36
HTR2B P41595 1/20 0.36
CHRNA4 P43681 1/20 0.36
MAPK1 P28482 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
POLB P06746 1/20 0.35
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16062870 0.89 ESR1 (0.36)
SCHEMBL17529792 0.84 TAAR1 (0.38) TAAR1IDO1AGXTKDM4ETHRB
SCHEMBL2956037 0.83 CA1 (0.32)
SCHEMBL27094922 0.83 HRH3 (0.37) TAAR1IDO1AGXTKDM4ESMN1; SMN2
SCHEMBL12458730 0.81 ESR1 (0.50)
SCHEMBL987484 0.81 AGXT (0.40) TAAR1IDO1AGXTTDP1SMN1; SMN2
SCHEMBL2951509 0.80 AKT1 (0.32) TAAR1
SCHEMBL9688030 0.80 TAAR1 (0.42) TAAR1IDO1AGXTKDM4ETHRB
SCHEMBL17529874 0.79 ESR1 (0.30)
SCHEMBL9227334 0.79 TAAR1 (0.41) TAAR1IDO1AGXTTDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11623895-B2 Water-repellent concrete admixture THE EUCLID CHEMICAL COMPANY (US) 2023-04-11 US disclosed
EP-2990112-B1 METHOD FOR MANUFACTURING CATALYST FOR SYNTHESIZING CYCLIC CARBONATE MARUZEN PETROCHEM CO LTD (JP) 2020-03-25 EP disclosed
EP-2990113-B1 METHOD FOR PRODUCING CATALYST FOR CYCLIC CARBONATE SYNTHESIS MARUZEN PETROCHEM CO LTD (JP) 2020-03-25 EP disclosed
US-10221200-B2 Quaternary amino alcohol functional organosilicon compounds, composition containing the latter and their production and use EVONIK DEGUSSA GMBH (DE) 2019-03-05 US disclosed
US-10029241-B2 Method for producing catalyst for cyclic carbonate synthesis MARUZEN PETROCHEMICAL CO., LTD. (JP) 2018-07-24 US disclosed
US-10011621-B2 Method for producing silica gel-immobolized phosphonium salt catalysts MARUZEN PETROCHEMICAL CO., LTD. (JP) 2018-07-03 US disclosed
CN-105163853-B The manufacturing method of cyclic carbonate catalyst for synthesizing 丸善石油化学株式会社 2018-06-12 CN disclosed
US-9834536-B2 Method for producing catalyst for cyclic carbonate synthesis NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2017-12-05 US disclosed
US-9796738-B2 Quaternary amino alcohol functional organosilicon compounds, composition containing the latter and their production and use EVONIK DEGUSSA GMBH (DE) 2017-10-24 US disclosed
CN-105121013-B The manufacture method of cyclic carbonate catalyst for synthesizing 丸善石油化学株式会社 2017-10-20 CN disclosed
EP-0418254-A1 TREATMENT OF SURFACES AND SURFACE LAYERS PÜHRINGER, Josef, Dr. (SE) 1991-03-27 EP disclosed
EP-0412515-A1 Buffered silane emulsions having low volatile organic compounds when cured PCR GROUP INC. (US) 1991-02-13 EP disclosed
US-4990377-A Waterproofing coatings for porous substrates, e.g. cements; storage stability; nonhydrolyzig PCR GROUP, INC. (US) 1991-02-05 US disclosed
US-4889747-A IN BUFFERED AQUEOUS SILANE EMULSION PCR, INC. (US) 1989-12-26 US disclosed
EP-0340816-A2 Buffered silane emulsions for rendering porous substrates water repellent PCR GROUP, INC. (US) 1989-11-08 EP disclosed
WO-1989010386-A1 TREATMENT OF SURFACES AND SURFACE LAYERS PUEHRINGER JOSEF (SE) 1989-11-02 WO disclosed
US-4877654-A STORAGE STABILITY PCR, INC. (US) 1989-10-31 US disclosed
EP-0234024-A1 Aqueous systems containing silanes for rendering masonry surfaces water repellant PCR GROUP, INC. (US) 1987-09-02 EP disclosed
US-4648904-A Aqueous systems containing silanes for rendering masonry surfaces water repellant SCM CORPORATION (US) 1987-03-10 US disclosed
US-4390712-A Aqueous solution of cationic organosilicon compounds and process for the production of the solutions DEGUSSA AG (DE) 1983-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10029241-B2 Method for producing catalyst for cyclic carbonate synthesis CYCS, CA7, CA9 TAAR1 4236/4885IDO1 4129/4885AGXT 1395/4885
US-10011621-B2 Method for producing silica gel-immobolized phosphonium salt catalysts SIK2, SIK3, SIK1 TAAR1 452/4885IDO1 2583/4885AGXT 970/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.