SCHEMBL3204232

SCHEMBL3204232

CCC(=Cc1ccc(OCC(O)COC(C)C)cc1Oc1ncc(C(F)(F)F)cc1Cl)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PPARG P37231 13/20 0.48
SMN1; SMN2 Q16637 2/20 0.44
FFAR1 O14842 1/20 0.43
LMNA P02545 1/20 0.43
LIPE Q05469 1/20 0.41
ALDH1A1 P00352 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3204229 1.00 PPARG (0.48) PPARGSMN1; SMN2FFAR1LMNALIPE
SCHEMBL3216134 0.86 PPARG (0.56) PPARGSMN1; SMN2FFAR1LMNALIPE
SCHEMBL3216121 0.86 PPARG (0.56) PPARGSMN1; SMN2FFAR1LMNALIPE
SCHEMBL3204219 0.83 PPARG (0.55) PPARGSMN1; SMN2FFAR1LMNA
SCHEMBL3211045 0.83 PPARG (0.64) PPARG
SCHEMBL3211029 0.83 PPARG (0.64) PPARG
SCHEMBL3217723 0.83 PPARG (0.50) PPARGSMN1; SMN2FFAR1LMNALIPE
SCHEMBL3217716 0.83 PPARG (0.50) PPARGSMN1; SMN2FFAR1LMNALIPE
SCHEMBL3202556 0.78 PPARG (0.82) PPARG
SCHEMBL3202569 0.78 PPARG (0.82) PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100041892-A1 Therapeutic agent for diabetes ABE HIDENORI 2010-02-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100041892-A1 Therapeutic agent for diabetes FABP4, SLC5A1, SLC5A2 PPARG 31/4885SMN1; SMN2 3845/4885FFAR1 227/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.