SCHEMBL3204285

SCHEMBL3204285

CC(O)c1c(C2=CC=CC2)ccc2ccccc12

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
UGT2B7 P16662 1/20 0.33
NCEH1 Q6PIU2 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
PTPN22 Q9Y2R2 1/20 0.33
DNMT1 P26358 1/20 0.32
ALDH1A1 P00352 2/20 0.31
CYP2A6 P11509 1/20 0.31
TSHR P16473 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
KDM4E B2RXH2 2/20 0.30
ALOX5 P09917 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3213819 0.85 MEN1 (0.32) MEN1KMT2AALDH1A1KDM4EHTT
SCHEMBL3203269 0.85 LMNA (0.41) MEN1KMT2AALDH1A1KDM4E
Hydrochloric Acid SCHEMBL3202052 0.81 NCEH1 (0.31) NCEH1KDM4EHTT
Hydrochloric Acid SCHEMBL3202043 0.81 DNMT1 (0.32) NCEH1DNMT1
SCHEMBL3191514 0.77 NCEH1 (0.32) UGT2B7NCEH1MEN1KMT2APTPN22
SCHEMBL9671120 0.76 DNMT1 (0.40) MEN1KMT2ADNMT1ALDH1A1CYP2A6
SCHEMBL2045558 0.76 TSHR (0.46) NCEH1DNMT1ALDH1A1CYP2A6TSHR
SCHEMBL783509 0.75 TSHR (0.44) NCEH1DNMT1ALDH1A1CYP2A6TSHR
SCHEMBL3204758 0.75 HSD17B10 (0.38) MEN1KMT2AALDH1A1CYP2A6TSHR
SCHEMBL3202707 0.74 NCEH1 (0.35) UGT2B7NCEH1MEN1KMT2APTPN22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1817837-B Carbonyl compound and method for preparing the same SUMITOMO CHEMICAL CO 2010-06-16 CN disclosed
US-7671226-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-02 US disclosed
EP-1426379-B1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME SUMITOMO CHEMICAL CO (JP) 2009-11-11 EP disclosed
US-7439379-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL CO., LTD. (JP) 2008-10-21 US disclosed
CN-100357303-C Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer using the same SUMITOMO CHEMICAL CO (JP) 2007-12-26 CN disclosed
CN-1817837-A Substituted cyclopentadiene and method for producing the same SUMITOMO CHEMICAL CO (JP) 2006-08-16 CN disclosed
CN-1578783-A Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer using the same SUMITOMO CHEMICAL CO (JP) 2005-02-09 CN disclosed
US-20040242410-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-02 US disclosed
EP-1426379-A1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME Sumitomo Chemical Company, Limited (JP) 2004-06-09 EP disclosed