Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20434835 | 0.81 | PDK1 (0.33) | PDK1PDK2PDK3PDK4 | |
| SCHEMBL8518512 | 0.79 | PDK1 (0.36) | PDK1PDK2PDK3PDK4 | |
| SCHEMBL664429 | 0.78 | PDK1 (0.30) | PDK1PDK2PDK3PDK4 | |
| SCHEMBL6114332 | 0.75 | — | — | |
| SCHEMBL10329837 | 0.74 | PDK1 (0.36) | PDK1PDK2PDK3PDK4 | |
| SCHEMBL2687661 | 0.74 | PDK1 (0.36) | PDK1PDK2PDK3PDK4 | |
| SCHEMBL16247993 | 0.74 | PDK1 (0.36) | PDK1PDK2PDK3PDK4 | |
| SCHEMBL13248360 | 0.74 | PDK1 (0.36) | PDK1PDK2PDK3PDK4 | |
| SCHEMBL7051330 | 0.74 | — | — | |
| SCHEMBL22694798 | 0.73 | PDK1 (0.34) | PDK1PDK2PDK3PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2198869-B1 | TREHALOSE FOR THE TREATMENT OR PREVENTION OF VASOSPASM | NEXT 21 K K (JP) | 2015-09-16 | — | — | EP | disclosed |
| US-8283337-B2 | Therapeutic or prophylactic agent for vasoconstriction | NEXT21 K.K. (JP) | 2012-10-09 | — | — | US | disclosed |
| EP-2198869-A1 | THERAPEUTIC OR PROPHYLACTIC AGENT FOR VASOCONSTRICTION | Next 21 K.K. (JP) | 2010-06-23 | — | — | EP | disclosed |
| US-20100035837-A1 | THERAPEUTIC OR PROPHYLACTIC AGENT FOR VASOCONSTRICTION | NEXT21 K.K. (JP) | 2010-02-11 | — | — | US | disclosed |