Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | WDR5 | P61964 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | ENGASE | Q8NFI3 | 3/20 | 0.57 |
| ▸ | SARM1 | Q6SZW1 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.57 |
| ▸ | NPY1R | P25929 | 2/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2363618 | 0.84 | MAPT (0.54) | NPC1RAB9AMAPTCYP2C9ALDH1A1 | |
| SCHEMBL30052062 | 0.83 | CYP2C9 (0.63) | NPC1RAB9AMAPTCYP2C9ALDH1A1 | |
| SCHEMBL106666 | 0.83 | CYP2C9 (0.63) | NPC1RAB9AMAPTCYP2C9ALDH1A1 | |
| SCHEMBL1269347 | 0.82 | CYP2C9 (0.61) | NPC1RAB9AMAPTCYP2C9ALDH1A1 | |
| SCHEMBL2364997 | 0.81 | CYP2C9 (0.60) | NPC1RAB9AMAPTCYP2C9ALDH1A1 | |
| 1,4-Butanediol SCHEMBL2365476 | 0.77 | CYP2C9 (0.55) | NPC1RAB9AMAPTCYP2C9ALDH1A1 | |
| SCHEMBL29323859 | 0.76 | CYP2C9 (0.55) | NPC1RAB9AMAPTCYP2C9ALDH1A1 | |
| Propylene Glycol SCHEMBL2364761 | 0.75 | CYP2C9 (0.54) | NPC1RAB9AMAPTCYP2C9ALDH1A1 | |
| Ethylene Glycol SCHEMBL2364760 | 0.75 | CYP2C9 (0.53) | NPC1RAB9AMAPTCYP2C9ALDH1A1 | |
| SCHEMBL14988972 | 0.74 | MAPT (0.57) | NPC1RAB9AMAPTCYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7683080-B2 | Stable iansoprazole containing more than 500 ppm, up to about 3,000 ppm water and more than 200 ppm, up to about 5,000 ppm alcohol | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2010-03-23 | — | — | US | claimed |
| US-7683080-B2 | Stable iansoprazole containing more than 500 ppm, up to about 3,000 ppm water and more than 200 ppm, up to about 5,000 ppm alcohol | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2010-03-23 | — | — | US | disclosed |