Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | WDR5 | P61964 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | ENGASE | Q8NFI3 | 3/20 | 0.55 |
| ▸ | SARM1 | Q6SZW1 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | ATP1A1 | P05023 | 3/20 | 0.55 |
| ▸ | ATP1B1 | P05026 | 3/20 | 0.55 |
| ▸ | ATP1A3 | P13637 | 3/20 | 0.55 |
| ▸ | ATP1B2 | P14415 | 3/20 | 0.55 |
| ▸ | ATP4A | P20648 | 3/20 | 0.55 |
| ▸ | ATP1A2 | P50993 | 3/20 | 0.55 |
| ▸ | ATP4B | P51164 | 3/20 | 0.55 |
| ▸ | ATP1B3 | P54709 | 3/20 | 0.55 |
| ▸ | FXYD2 | P54710 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30052062 | 0.93 | CYP2C9 (0.63) | CYP2C9MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL106666 | 0.93 | CYP2C9 (0.63) | CYP2C9MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL23988420 | 0.85 | CYP2C9 (0.51) | CYP2C9MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL1269347 | 0.83 | CYP2C9 (0.61) | CYP2C9MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL1307379 | 0.83 | KMT2A (0.63) | CYP2C9MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL30905609 | 0.83 | KMT2A (0.63) | CYP2C9MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL29272563 | 0.82 | CYP2C9 (0.43) | CYP2C9MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL6600434 | 0.82 | KMT2A (0.62) | CYP2C9MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL6600439 | 0.82 | CYP2C9 (0.62) | CYP2C9MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL8503970 | 0.81 | KMT2A (0.45) | CYP2C9MAPTNPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240238264-A1 | INHIBITORS OF SARM1 NADASE ACTIVITY AND USES THEREOF | DISARM THERAPEUTICS, INC. | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240238264-A1 | INHIBITORS OF SARM1 NADASE ACTIVITY AND USES THEREOF | SARM1, NADK, NNMT | CYP2C9 4424/4885MAPT 242/4885NPC1 209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.