SCHEMBL32048897

SCHEMBL32048897

O=C(Nc1ccc(F)cc1)N1CCc2ccccc2[C@H]1c1ccc(C(F)(F)F)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 13/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3052759 1.00 TRPM8 (1.00) TRPM8
SCHEMBL31518948 1.00 TRPM8 (1.00) TRPM8
SCHEMBL3073338 1.00 TRPM8 (1.00) TRPM8
SCHEMBL3052746 0.93 TRPM8 (0.86) TRPM8
SCHEMBL3062025 0.90 TRPM8 (1.00) TRPM8
SCHEMBL3074683 0.90 TRPM8 (1.00) TRPM8
SCHEMBL3066858 0.90 TRPM8 (1.00) TRPM8
SCHEMBL3061851 0.90 TRPM8 (0.81) TRPM8
SCHEMBL3056733 0.90 TRPM8 (0.81) TRPM8
SCHEMBL3075245 0.88 TRPM8 (1.00) TRPM8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122030505-A Use of TRPM8 inhibitors for improving animal productivity in cold conditions and method 中国科学院动物研究所 2026-05-15 CN claimed