Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1132445 | 0.91 | TSHR (0.43) | TSHRALDH1A1TDP1LMNAADRB2 | |
| SCHEMBL1223971 | 0.89 | TSHR (0.44) | TSHRALDH1A1TDP1 | |
| SCHEMBL17529658 | 0.89 | TSHR (0.44) | TSHRALDH1A1TDP1 | |
| SCHEMBL17529728 | 0.89 | TSHR (0.44) | TSHRALDH1A1TDP1 | |
| SCHEMBL1003519 | 0.89 | TSHR (0.44) | TSHRALDH1A1TDP1 | |
| SCHEMBL15333743 | 0.89 | LMNA (0.38) | TSHRALDH1A1LMNAADRB2ADRB1 | |
| SCHEMBL15332691 | 0.89 | LMNA (0.38) | TSHRALDH1A1LMNAADRB2ADRB1 | |
| SCHEMBL15333333 | 0.89 | LMNA (0.38) | TSHRALDH1A1LMNAADRB2ADRB1 | |
| SCHEMBL15332983 | 0.89 | LMNA (0.38) | TSHRALDH1A1LMNAADRB2ADRB1 | |
| SCHEMBL15333151 | 0.89 | LMNA (0.38) | TSHRALDH1A1LMNAADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10221200-B2 | Quaternary amino alcohol functional organosilicon compounds, composition containing the latter and their production and use | EVONIK DEGUSSA GMBH (DE) | 2019-03-05 | — | — | US | disclosed |
| US-9796738-B2 | Quaternary amino alcohol functional organosilicon compounds, composition containing the latter and their production and use | EVONIK DEGUSSA GMBH (DE) | 2017-10-24 | — | — | US | disclosed |
| US-20170233416-A1 | Quaternary amino alcohol functional organosilicon compounds, composition containing the latter and their production and use | EVONIK DEGUSSA GMBH (DE) | 2017-08-17 | — | — | US | disclosed |
| EP-2590988-B1 | QUATERNARY AMINO ALCOHOL FUNCTIONAL ORGANOSILICON COMPOUNDS, COMPOSITION CONTAINING THE LATTER AND THEIR PRODUCTION AND USE | EVONIK DEGUSSA GMBH (DE) | 2017-03-01 | — | — | EP | disclosed |
| EP-2421874-B1 | COMPOSITION CONTAINING QUATERNARY AMINO-FUNCTIONAL ORGANOSILICON COMPOUNDS AND PRODUCTION AND USE THEREOF | EVONIK DEGUSSA GMBH (DE) | 2015-09-30 | — | — | EP | disclosed |
| US-8980960-B2 | Methods for producing a dispersion containing silicon dioxide particles and cationization agent | EVONIK DEGUSSA GMBH (DE) | 2015-03-17 | — | — | US | disclosed |
| US-8979996-B2 | Composition containing quaternary amino-functional organosilicon compunds and production and use thereof | EVONIK DEGUSSA GMBH (DE) | 2015-03-17 | — | — | US | disclosed |
| US-20140208981-A1 | COMPOSITION CONTAINING QUATERNARY AMINO-FUNCTIONAL ORGANOSILICON COMPOUNDS AND PRODUCTION AND USE THEREOF | EVONIK DEGUSSA GMBH (DE) | 2014-07-31 | — | — | US | disclosed |
| US-8747541-B2 | Dispersion containing silica particles surface-modified with quaternary, aminofunctional organosilicon compounds | EVONIK DEGUSSA GMBH (DE) | 2014-06-10 | — | — | US | disclosed |
| US-8728225-B2 | Composition containing quaternary amino-functional organosilicon compounds and production and use thereof | EVONIK DEGUSSA GMBH (DE) | 2014-05-20 | — | — | US | disclosed |
| EP-2421874-A1 | COMPOSITION CONTAINING QUATERNARY AMINO-FUNCTIONAL ORGANOSILICON COMPOUNDS AND PRODUCTION AND USE THEREOF | Evonik Degussa GmbH (DE) | 2012-02-29 | — | — | EP | disclosed |
| US-20120037040-A1 | COMPOSITION CONTAINING QUATERNARY AMINO-FUNCTIONAL ORGANOSILICON COMPOUNDS AND PRODUCTION AND USE THEREOF | EVONIK DEGUSSA GMBH (DE) | 2012-02-16 | — | — | US | disclosed |
| WO-2012004044-A1 | METHODS FOR PRODUCING A DISPERSION CONTAINING SILICON DIOXIDE PARTICLES AND CATIONIZATION AGENT | EVONIK DEGUSSA GMBH (DE) | 2012-01-12 | — | — | WO | disclosed |
| WO-2012004082-A2 | QUATERNARY AMINO ALCOHOL FUNCTIONAL ORGANOSILICON COMPOUNDS, COMPOSITION CONTAINING THE LATTER AND THEIR PRODUCTION AND USE | EVONIK DEGUSSA GMBH (DE) | 2012-01-12 | — | — | WO | disclosed |
| US-20120006228-A1 | DISPERSION CONTAINING SILICA PARTICLES SURFACE-MODIFIED WITH QUATERNARY, AMINOFUNCTIONAL ORGANOSILICON COMPOUNDS | EVONIK DEGUSSA GMBH (DE) | 2012-01-12 | — | — | US | disclosed |
| WO-2010121878-A1 | DISPERSION CONTAINING SILICA PARTICLES SURFACE-MODIFIED WITH QUATERNARY, AMINOFUNCTIONAL ORGANOSILICON COMPOUNDS | EVONIK DEGUSSA GMBH (DE) | 2010-10-28 | — | — | WO | disclosed |
| WO-2010121873-A1 | COMPOSITION CONTAINING QUATERNARY AMINO-FUNCTIONAL ORGANOSILICON COMPOUNDS AND PRODUCTION AND USE THEREOF | EVONIK DEGUSSA GMBH (DE) | 2010-10-28 | — | — | WO | disclosed |
| EP-0054748-B1 | PROCESS FOR THE PREPARATION OF AQUEOUS SOLUTIONS OF CATIONIC ORGANOSILICIUM COMPOUNDS | Degussa Aktiengesellschaft (DE) | 1984-09-26 | — | — | EP | disclosed |
| US-4390712-A | Aqueous solution of cationic organosilicon compounds and process for the production of the solutions | DEGUSSA AG (DE) | 1983-06-28 | — | — | US | disclosed |
| EP-0054748-A2 | Process for the preparation of aqueous solutions of cationic organosilicium compounds | Degussa Aktiengesellschaft (DE) | 1982-06-30 | — | — | EP | disclosed |