SCHEMBL3205380

SCHEMBL3205380

C(=NNc1ccccc1)c1ccccc1C1c2ccccc2-c2ccccc21

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 11/20 0.54
MEN1 O00255 9/20 0.54
KMT2A Q03164 9/20 0.54
GAA P10253 8/20 0.54
HPGD P15428 5/20 0.54
ALDH1A1 P00352 5/20 0.54
GFER P55789 1/20 0.54
NOX1 Q9Y5S8 2/20 0.49
SENP7 Q9BQF6 3/20 0.44
RAB9A P51151 6/20 0.42
LMNA P02545 4/20 0.42
SMN1; SMN2 Q16637 5/20 0.42
KDM4E B2RXH2 4/20 0.42
MAPK1 P28482 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
NPC1 O15118 5/20 0.39
ALOX12 P18054 1/20 0.38
CASP3 P42574 2/20 0.38
SENP8 Q96LD8 1/20 0.38
SENP6 Q9GZR1 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3205379 1.00 MAPT (0.54) MAPTMEN1KMT2AGAAHPGD
SCHEMBL3199787 0.83 KMT2A (0.53) MAPTMEN1KMT2AGAAHPGD
SCHEMBL3199781 0.83 KMT2A (0.53) MAPTMEN1KMT2AGAAHPGD
SCHEMBL3193810 0.79 MAPT (0.45) MAPTMEN1KMT2AGAAHPGD
SCHEMBL3193822 0.79 MAPT (0.45) MAPTMEN1KMT2AGAAHPGD
SCHEMBL3199796 0.77 MEN1 (0.43) MAPTMEN1KMT2AGAAHPGD
SCHEMBL3199085 0.77 MAPT (0.37) MAPTMEN1KMT2AGAAHPGD
SCHEMBL3679278 0.77 MAPT (0.47) MAPTMEN1KMT2AGAAHPGD
SCHEMBL3199081 0.77 MAPT (0.37) MAPTMEN1KMT2AGAAHPGD
SCHEMBL3679280 0.77 MAPT (0.47) MAPTMEN1KMT2AGAAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1817837-B Carbonyl compound and method for preparing the same SUMITOMO CHEMICAL CO 2010-06-16 CN disclosed
US-7671226-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-02 US disclosed
EP-1426379-B1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME SUMITOMO CHEMICAL CO (JP) 2009-11-11 EP disclosed
US-7439379-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL CO., LTD. (JP) 2008-10-21 US disclosed
CN-100357303-C Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer using the same SUMITOMO CHEMICAL CO (JP) 2007-12-26 CN disclosed
CN-1817837-A Substituted cyclopentadiene and method for producing the same SUMITOMO CHEMICAL CO (JP) 2006-08-16 CN disclosed