SCHEMBL3199796

SCHEMBL3199796

C(=NNc1cccc2ccccc12)c1ccccc1C1c2ccccc2-c2ccccc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 9/20 0.43
KMT2A Q03164 9/20 0.43
MAPT P10636 7/20 0.43
GAA P10253 7/20 0.43
SMN1; SMN2 Q16637 7/20 0.43
NPC1 O15118 5/20 0.43
KDM4E B2RXH2 5/20 0.43
RAB9A P51151 5/20 0.43
TDP1 Q9NUW8 4/20 0.43
LMNA P02545 4/20 0.42
HTT P42858 3/20 0.42
HPGD P15428 2/20 0.40
NFKB1 P19838 1/20 0.40
NFKB2 Q00653 1/20 0.40
RELA Q04206 1/20 0.40
ALDH1A1 P00352 4/20 0.38
MGAM O43451 1/20 0.37
SI P14410 1/20 0.37
MGAM2 Q2M2H8 1/20 0.37
POLB P06746 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3193822 0.81 MAPT (0.45) MEN1KMT2AMAPTGAASMN1; SMN2
SCHEMBL3193810 0.81 MAPT (0.45) MEN1KMT2AMAPTGAASMN1; SMN2
SCHEMBL3208577 0.80 MAPT (0.43) MEN1KMT2AMAPTGAASMN1; SMN2
SCHEMBL3206153 0.78 GAA (0.39) MEN1KMT2AMAPTGAASMN1; SMN2
SCHEMBL3215907 0.77 MEN1 (0.40) MEN1KMT2AMAPTGAASMN1; SMN2
SCHEMBL3205379 0.77 MAPT (0.54) MEN1KMT2AMAPTGAASMN1; SMN2
SCHEMBL3205380 0.77 MAPT (0.54) MEN1KMT2AMAPTGAASMN1; SMN2
SCHEMBL3199781 0.76 KMT2A (0.53) MEN1KMT2AMAPTGAASMN1; SMN2
SCHEMBL3199787 0.76 KMT2A (0.53) MEN1KMT2AMAPTGAASMN1; SMN2
SCHEMBL3682816 0.73 MEN1 (0.40) MEN1KMT2AMAPTGAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7671226-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-02 US disclosed
EP-1426379-B1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME SUMITOMO CHEMICAL CO (JP) 2009-11-11 EP disclosed
US-7439379-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL CO., LTD. (JP) 2008-10-21 US disclosed