Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 6/20 | 0.48 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14198165 | 0.90 | CRHR1 (0.47) | CRHR1LMNAHTTNPSR1POLB | |
| SCHEMBL3207756 | 0.89 | CRHR1 (0.48) | CRHR1PTGES2LMNAHTTNPSR1 | |
| SCHEMBL13423132 | 0.81 | CRHR1 (0.46) | CRHR1PTGES2 | |
| SCHEMBL3211954 | 0.78 | CRHR1 (0.72) | CRHR1 | |
| SCHEMBL2056029 | 0.74 | CRHR1 (0.53) | CRHR1LMNAPOLBKDM4EALDH1A1 | |
| SCHEMBL13423135 | 0.73 | CRHR1 (0.53) | CRHR1PTGES2LMNAHTTNPSR1 | |
| SCHEMBL2055982 | 0.72 | CRHR1 (0.70) | CRHR1HTTALDH1A1HPGDL3MBTL1 | |
| SCHEMBL2056017 | 0.72 | CRHR1 (0.63) | CRHR1LMNAKDM4EALDH1A1RAB9A | |
| SCHEMBL2056027 | 0.72 | CRHR1 (0.81) | CRHR1LMNAHTTNPSR1POLB | |
| SCHEMBL2056030 | 0.71 | CRHR1 (0.51) | CRHR1LMNAHTTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118459363-B | Fluorine substituted proliferation cell nuclear antigen inhibitor and preparation method and application thereof | 安徽贝克制药股份有限公司 | 2024-12-17 | — | — | CN | claimed |
| CN-118546074-A | Deuterated proliferation cell nuclear antigen inhibitor and preparation method and application thereof | 安徽贝克制药股份有限公司 | 2024-08-27 | — | — | CN | claimed |
| CN-118459363-A | Fluorine substituted proliferation cell nuclear antigen inhibitor and preparation method and application thereof | 安徽贝克制药股份有限公司 | 2024-08-09 | — | — | CN | claimed |
| CN-118459363-B | Fluorine substituted proliferation cell nuclear antigen inhibitor and preparation method and application thereof | 安徽贝克制药股份有限公司 | 2024-12-17 | — | — | CN | disclosed |
| CN-118546074-A | Deuterated proliferation cell nuclear antigen inhibitor and preparation method and application thereof | 安徽贝克制药股份有限公司 | 2024-08-27 | — | — | CN | disclosed |
| CN-118459363-A | Fluorine substituted proliferation cell nuclear antigen inhibitor and preparation method and application thereof | 安徽贝克制药股份有限公司 | 2024-08-09 | — | — | CN | disclosed |
| EP-1369221-B9 | SUCCESSIVELY BIAXIAL-ORIENTED POROUS POLYPROPYLENE FILM AND PROCESS FOR PRODUCTION THEREOF | NEW JAPAN CHEM CO LTD (JP) | 2010-12-29 | — | — | EP | disclosed |
| US-7682689-B2 | A polypropylene-based resin and a beta-crystal nucleating agent having a film thickness uniformity of < 0.1 and the film exhibiting good stability; high air-permeability and porosity; good feeling and electrical resistance required for a battery separator; industrial scale; | NEW JAPAN CHEMICAL CO., LTD. (JP) | 2010-03-23 | — | — | US | disclosed |
| US-20100056515-A1 | BENZIMIDAZOLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-03-04 | — | — | US | disclosed |
| EP-1369221-B1 | SUCCESSIVELY BIAXIAL-ORIENTED POROUS POLYPROPYLENE FILM AND PROCESS FOR PRODUCTION THEREOF | NEW JAPAN CHEM CO LTD (JP) | 2009-11-11 | — | — | EP | disclosed |
| EP-2088861-A2 | BENZIMIDAZOLE COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2009-08-19 | — | — | EP | disclosed |
| WO-2008051533-A2 | BENZIMIDAZOLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-02 | — | — | WO | disclosed |
| US-20070269719-A1 | A polypropylene-based resin and a beta-crystal nucleating agent having a film thickness uniformity of < 0.1 and the film exhibiting good stability; high air-permeability and porosity; good feeling and electrical resistance required for a battery separator; industrial scale; | NEW JAPAN CHEMICAL CO., LTD. (JP) | 2007-11-22 | — | — | US | disclosed |
| US-7235203-B2 | Successively biaxial-oriented porous polypropylene film and process for production thereof | NEW JAPAN CHEMICAL CO., LTD. (JP) | 2007-06-26 | — | — | US | disclosed |
| US-20040096744-A1 | Extrusion from melt, stretching; mixture of polypropylene and nucleation | NEW JAPAN CHEMCIAL CO., LTD. (JP) | 2004-05-20 | — | — | US | disclosed |
| EP-1369221-A1 | SUCCESSIVELY BIAXIAL-ORIENTED POROUS POLYPROPYLENE FILM AND PROCESS FOR PRODUCTION THEREOF | NEW JAPAN CHEMICAL CO.,LTD. (JP) | 2003-12-10 | — | — | EP | disclosed |
| EP-0251784-A2 | Naphthalenylsulfonylimidazolidinediones and their thioxo analogs | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056515-A1 | BENZIMIDAZOLE COMPOUNDS | HRH4, SSTR5, CNR1 | CRHR1 4/4885PTGES2 3390/4885LMNA 4357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.