Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL3205919

CCCN(C)c1ccccc1.N

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
TAAR1 Q96RJ0 3/20 0.43
TP53 P04637 1/20 0.42
SIGMAR1 Q99720 1/20 0.41
ESR1 P03372 1/20 0.40
MEN1 O00255 1/20 0.39
HTT P42858 1/20 0.39
KMT2A Q03164 1/20 0.39
MAPT P10636 1/20 0.39
TSHR P16473 2/20 0.39
ALDH1A1 P00352 1/20 0.39
GLA P06280 1/20 0.39
TRPV1 Q8NER1 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21676 0.98 CA12 (0.45) CA12CA2CA9TAAR1TP53
Hydrochloric Acid SCHEMBL27301016 0.95 CA12 (0.44) CA12CA2CA9TAAR1TP53
Ammonia Solution, Strong SCHEMBL11366087 0.86 MAPT (0.53) CA12CA2CA9TAAR1TP53
SCHEMBL11044440 0.85 CA12 (0.50) CA12CA2CA9TAAR1SIGMAR1
SCHEMBL96161 0.84 MAPT (0.55) CA12CA2CA9TAAR1TP53
SCHEMBL94623 0.82 NPC1 (0.49) CA12CA2CA9SIGMAR1MAPT
Hydrochloric Acid SCHEMBL8801549 0.82 MAPT (0.53) CA12CA2CA9TAAR1TP53
SCHEMBL13481182 0.81 ALDH1A1 (0.48) TAAR1SIGMAR1HTTTSHRALDH1A1
SCHEMBL94910 0.80 NPC1 (0.51) SIGMAR1MAPTTRPV1
SCHEMBL6501802 0.80 NPC1 (0.51) SIGMAR1MAPTTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7678850-B2 Pigment dispersions containing aminated acrylic macromonomer dispersant E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-03-16 US disclosed
US-20090012231-A1 PIGMENT DISPERSIONS CONTAINING AMINATED ACRYLIC MACROMONOMER DISPERSANT E. I. DU PONT DE NEMOURS AND COMPANY 2009-01-08 US disclosed
EP-1966335-A2 PIGMENT DISPERSIONS CONTAINING AMINATED ACRYLIC MACROMONOMER DISPERSANT E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-09-10 EP disclosed
WO-2007070724-A2 PIGMENT DISPERSIONS CONTAINING AMINATED ACRYLIC MACROMONOMER DISPERSANT E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-06-21 WO disclosed
US-20070142546-A1 Pigment dispersions containing aminated acrylic macromonomer dispersant AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) 2007-06-21 US disclosed