Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Styrene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | TSHR | P16473 | 2/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Styrene SCHEMBL11688868 | 0.98 | ALDH1A1 (0.67) | ALDH1A1TSHRTDP1TP53HDAC8 | |
| Styrene SCHEMBL9614429 | 0.95 | ALDH1A1 (0.64) | ALDH1A1TSHRTDP1TP53HDAC8 | |
| Styrene SCHEMBL8333425 | 0.91 | ALDH1A1 (0.64) | ALDH1A1TSHRTDP1TP53HDAC8 | |
| Styrene SCHEMBL28211071 | 0.90 | ALDH1A1 (0.78) | ALDH1A1TSHRTDP1TP53HDAC8 | |
| Styrene SCHEMBL16279238 | 0.89 | ALDH1A1 (0.56) | ALDH1A1TSHRTDP1TP53HDAC8 | |
| Styrene SCHEMBL385205 | 0.87 | ALDH1A1 (0.74) | ALDH1A1TSHRTDP1TP53HDAC8 | |
| Styrene SCHEMBL290213 | 0.87 | ALDH1A1 (0.74) | ALDH1A1TSHRTDP1TP53HDAC8 | |
| Styrene SCHEMBL93585 | 0.87 | ALDH1A1 (0.74) | ALDH1A1TSHRTDP1TP53HDAC8 | |
| Styrene SCHEMBL27596753 | 0.87 | ALDH1A1 (0.82) | ALDH1A1TSHRTDP1TP53HDAC8 | |
| Styrene SCHEMBL6829874 | 0.87 | ALDH1A1 (0.82) | ALDH1A1TSHRTDP1TP53HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119095929-A | Sealing gasket for crown caps with reduced sheet metal hardness | 阿克泰加DS有限公司 | 2024-12-06 | — | — | CN | claimed |
| CN-118459876-A | Puncture-resistant scald-resistant pre-laid waterproof coiled material and preparation method thereof | 建国伟业防水科技望都有限公司 | 2024-08-09 | — | — | CN | claimed |
| CN-117925057-B | Preparation method of vinyl anti-corrosion resin coating | 江苏金隆新材料有限公司 | 2024-05-31 | — | — | CN | claimed |
| CN-117925057-A | Preparation method of vinyl anti-corrosion resin coating | 江苏金隆新材料有限公司 | 2024-04-26 | — | — | CN | claimed |
| CN-111807317-B | Preparation method and application of nano bridge for improving percolation system | 肇庆市华师大光电产业研究院 | 2024-03-19 | — | — | CN | claimed |
| CN-117624653-A | High-density carboxyl modified magnetic microsphere with hydrophilic surface and preparation method thereof | 北京唯公医疗技术有限公司 | 2024-03-01 | — | — | CN | claimed |
| CN-117380399-A | Beneficiation reagent for nickel-cobalt ore flotation and preparation method thereof | 西北矿冶研究院 | 2024-01-12 | — | — | CN | claimed |
| CN-116554382-A | High-temperature-resistant strong-acid ion exchange resin and preparation method and application thereof | 中国石油化工股份有限公司 | 2023-08-08 | — | — | CN | claimed |
| CN-116477950-A | SiC-MC composite ceramic precursor and preparation method of composite ceramic thereof | 中南大学 | 2023-07-25 | — | — | CN | claimed |
| CN-116041745-A | Surface epoxy group functionalized magnetic polystyrene microsphere and preparation method thereof | 深圳唯公生物科技有限公司 | 2023-05-02 | — | — | CN | claimed |
| CN-112996654-A | Device and method for the surface treatment of molded parts | 戴漫森有限责任公司 | 2021-06-18 | — | — | CN | claimed |
| CN-112376025-A | Method for adjusting near-infrared absorption peak wavelength of Ag-ITO composite material | 吉林师范大学 | 2021-02-19 | — | — | CN | claimed |
| CN-111807317-A | Preparation method and application of nano bridge for improving percolation system | 肇庆市华师大光电产业研究院 | 2020-10-23 | — | — | CN | claimed |
| CN-109326803-A | A kind of hydrogen fuel cell and preparation method thereof | 云南省能源研究院有限公司 | 2019-02-12 | — | — | CN | claimed |
| CN-108519363-A | A kind of Ag/Cu2S composite S ERS substrates and preparation method thereof | 吉林师范大学 | 2018-09-11 | — | — | CN | claimed |
| CN-108444973-A | One kind having the active Ag/FeS composite material and preparation methods of SERS | 吉林师范大学 | 2018-08-24 | — | — | CN | claimed |
| CN-105524298-B | A kind of compound art post paperboard special inorganic raw powder's production technology | 新昌县以琳环保科技有限公司 | 2018-05-29 | — | — | CN | claimed |
| CN-104607252-B | A kind of support type polystyrene sulfonic acid resin catalyst and preparation method thereof | 烟台大学 | 2016-09-14 | — | — | CN | claimed |
| CN-105837720-A | Resin filler for fracturing and its preparation method | 孙安顺 | 2016-08-10 | — | — | CN | claimed |
| CN-105524298-A | Preparation method of composite ivory board dedicated inorganic powder | CHENGDU NEW KELI CHEM SCI CO | 2016-04-27 | — | — | CN | claimed |