Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 8/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL285659 | 0.88 | ALDH1A1 (0.59) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| Ammonia Solution, Strong SCHEMBL11107036 | 0.86 | ALDH1A1 (0.57) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| Hydrochloric Acid SCHEMBL28271407 | 0.84 | ALDH1A1 (0.55) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| Dimethylamine SCHEMBL6114524 | 0.82 | ALDH1A1 (0.53) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| Ethylene Glycol SCHEMBL230725 | 0.82 | ALDH1A1 (0.59) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| Acrylic Acid Ethyl Ester SCHEMBL444412 | 0.80 | TSHR (0.50) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| Acrylic Acid Ethyl Ester SCHEMBL8027705 | 0.79 | TSHR (0.48) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL4632473 | 0.79 | ALDH1A1 (0.53) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| Acrylic Acid Ethyl Ester SCHEMBL15387422 | 0.79 | TSHR (0.48) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL15268464 | 0.78 | ALDH1A1 (0.48) | ALDH1A1TP53HIF1ACYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11013583-B2 | Three dimensional fabricating material systems and methods for producing layered dental products | DENTSPLY SIRONA INC. (US) | 2021-05-25 | — | — | US | disclosed |
| US-10639877-B2 | Three-dimensional printing systems for rapidly producing objects | DENTSPLY SIRONA INC. (US) | 2020-05-05 | — | — | US | disclosed |
| US-20190152097-A1 | THREE-DIMENSIONAL FABRICATING SYSTEMS FOR RAPIDLY PRODUCING OBJECTS | DENTSPLY SIRONA INC. (US) | 2019-05-23 | — | — | US | disclosed |
| US-20190053883-A1 | THREE DIMENSIONAL FABRICATING MATERIAL SYSTEMS AND METHODS FOR PRODUCING LAYERED DENTAL PRODUCTS | DENTSPLY SIRONA INC. (US) | 2019-02-21 | — | — | US | disclosed |
| US-20160332367-A1 | THREE-DIMENSIONAL PRINTING SYSTEMS FOR RAPIDLY PRODUCING OBJECTS | DENTSPLY SIRONA INC. (US) | 2016-11-17 | — | — | US | disclosed |
| US-20100044895-A1 | Method of forming a dental product | DENTSPLY INTERNATIONAL INC. | 2010-02-25 | — | — | US | disclosed |
| US-20090148813-A1 | Three-dimensional printing methods and materials for making dental products | SUN BENJAMIN J | 2009-06-11 | — | — | US | disclosed |
| US-20090130624-A1 | Methods and kits for making flexible dental guards | SUN BENJAMIN JIEMIN | 2009-05-21 | — | — | US | disclosed |
| US-4892478-A | Method of preparing dental appliances | DENTSPLY RESEARCH & DEVELOPMENT CORP. (US) | 1990-01-09 | — | — | US | disclosed |
| EP-0334256-A2 | Dental appliance preparation and material therefor | DENTSPLY INTERNATIONAL, INC. (US) | 1989-09-27 | — | — | EP | disclosed |