Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 3/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 9/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 9/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 9/20 | 0.51 |
| ▸ | CTSV | O60911 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | CTSC | P53634 | 1/20 | 0.49 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3218557 | 1.00 | CHRNA7 (0.58) | CHRNA7CHRM2CHRM1CHRM3CTSV | |
| SCHEMBL3222951 | 1.00 | CHRNA7 (0.58) | CHRNA7CHRM2CHRM1CHRM3CTSV | |
| Hydrochloric Acid SCHEMBL8988206 | 0.93 | CHRNA7 (0.52) | CHRNA7CHRM2CHRM1CHRM3CTSV | |
| SCHEMBL4197310 | 0.91 | CHRNA7 (0.53) | CHRNA7CHRM2CHRM1CHRM3 | |
| SCHEMBL9707154 | 0.87 | CHRNA7 (0.50) | CHRNA7CHRM2CHRM1CHRM3CYP2D6 | |
| Hydrochloric Acid SCHEMBL8988244 | 0.86 | CHRNA7 (0.49) | CHRNA7CHRM2CHRM1CHRM3CYP2D6 | |
| Hydrochloric Acid SCHEMBL8988338 | 0.86 | CHRNA7 (0.49) | CHRNA7CHRM2CHRM1CHRM3CYP2D6 | |
| Hydrochloric Acid SCHEMBL8988432 | 0.84 | CHRNA7 (0.50) | CHRNA7CHRM2CHRM1CHRM3CYP2D6 | |
| SCHEMBL3219330 | 0.84 | MEN1 (0.51) | CHRNA7CHRM2CHRM1CHRM3CHRM5 | |
| SCHEMBL3210416 | 0.84 | GLA (0.54) | CHRNA7CHRM2CHRM1CHRM3CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056565-A1 | Heterocyclic Derivatives as M3 Muscarinic Receptors | ARGENTA DISCOVERY LIMITED (GB) | 2010-03-04 | — | — | US | disclosed |
| EP-2121688-A1 | HETEROCYCLIC DERIVATIVES AS M3 MUSCARINIC RECEPTORS | Argenta Discovery Ltd (GB) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008099186-A1 | HETEROCYCLIC DERIVATIVES AS M3 MUSCARINIC RECEPTORS | ARGENTA DISCOVERY LIMITED (GB) | 2008-08-21 | — | — | WO | disclosed |
| US-4675326-A | MONO AND BIS-PYRIDINIUM OXIMES FOR ORGANOPHOSPHOROUS AND CARB AMATE POISONING | STATE OF ISRAEL, PRIME MINISTERS OFFICE, ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCH | 1987-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056565-A1 | Heterocyclic Derivatives as M3 Muscarinic Receptors | CHRM2, CHRM3, CHRM1 | CHRNA7 13/4885CHRM2 1/4885CHRM1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.