SCHEMBL320710

SCHEMBL320710

O=C(CCCc1ccccc1N1C(=O)C=CC1=O)ON1C(=O)CCC1=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 9/20 0.46
TLR9 Q9NR96 2/20 0.38
PSMB8 P28062 1/20 0.37
PSMB5 P28074 1/20 0.37
MAPK1 P28482 1/20 0.36
ALDH1A1 P00352 1/20 0.35
HSP90AA1 P07900 1/20 0.35
PKM P14618 1/20 0.35
CCR6 P51684 1/20 0.35
ATM Q13315 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
NR1H2 P55055 2/20 0.35
NR1H3 Q13133 2/20 0.35
KMT2A Q03164 2/20 0.34
MEN1 O00255 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
CYP4F2 P78329 1/20 0.33
CYP4A11 Q02928 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28349583 0.92 MGLL (0.41) MGLLTLR9PSMB8PSMB5MAPK1
SCHEMBL11030785 0.86 MGLL (0.51) MGLLTLR9PSMB8PSMB5MAPK1
SCHEMBL9055859 0.81 MGLL (0.37) MGLLTLR9FAAH
SCHEMBL157132 0.81 MGLL (0.37) MGLLTLR9FAAH
SCHEMBL11032205 0.78 GSK3A (0.43) MGLLTLR9PSMB8PSMB5MAPK1
SCHEMBL43979 0.78 MGLL (0.48) MGLLMAPK1ALDH1A1HSP90AA1PKM
SCHEMBL487779 0.77 MGLL (0.57) MGLLTLR9MAPK1ALDH1A1HSP90AA1
SCHEMBL8198691 0.76 MGLL (0.46) MGLLMAPK1ALDH1A1HSP90AA1PKM
SCHEMBL1231930 0.76 HDAC1 (0.50) MAPK1TDP1KMT2AMAPTSMN1; SMN2
SCHEMBL16819519 0.76 CYP4F2 (0.46) PSMB8PSMB5ALDH1A1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10953073-B2 XTEN conjugate compositions and methods of making same AMUNIX PHARMACEUTICALS, INC. (US) 2021-03-23 US claimed
US-20040014124-A1 Method for examining reactivity and method for detecting a complex CANON KABUSHIKI KAISHA (JP) 2004-01-22 US claimed
EP-1352976-A2 Method of spotting probe on solid support, probe array and method of manufacturing thereof, and method of detecting target substance and method of identifying structure of target substance using probe array CANON KABUSHIKI KAISHA (JP) 2003-10-15 EP claimed
US-20030190612-A1 Detecting method and detection substrate for use therein CANON KABUSHIKI KAISHA (JP) 2003-10-09 US claimed
EP-0895082-B1 Bubble jet method for spotting probes on a solid support and method of manufacturing probe arrays. CANON KK (JP) 2003-09-24 EP claimed
US-20030059817-A1 Spotting probe can bind preferentially to target nucleotide squences on solid support; provide liquid containing probe, deposit on solid support, form spot of probe on solid support OKAMOTO TADASHI (JP) 2003-03-27 US claimed
US-20030022227-A1 Hybridization substrate for use in genome analysis and bacterial detection RIKEN (JP) 2003-01-30 US claimed
EP-1279434-A2 Hybridization substrate, method of manufacturing same, and method of use for same Riken (JP) 2003-01-29 EP claimed
US-20020146715-A1 Spotting probe preferentially bound to solid support; obtain liquid containing probe, apply to surface of solid support, allow stain to form on solid support OKAMOTO TADASHI (JP) 2002-10-10 US claimed
EP-0895082-A2 Method of spotting probe on solid support, probe array and method of manufacturing thereof, and method of detecting target substance and method of identifying structure of target substance using probe array CANON KABUSHIKI KAISHA (JP) 1999-02-03 EP claimed
EP-4596719-A2 SYSTEMS AND METHODS FOR TARGETING DIROFILARIA IMMITIS AND DIROFILARIA REPENS Smith College (US) 2025-08-06 EP disclosed
EP-3959344-B1 A KIT FOR TARGETING DIROFILARIA IMMITIS SMITH COLLEGE (US) 2025-06-04 EP disclosed
US-12285476-B2 Amino acid sequence derived from S protein of SARS-CoV2 for generating an anti-SARS-CoV-2 antibody TOAGOSEI CO., LTD. (JP) 2025-04-29 US disclosed
WO-2025063100-A1 PEPTIDE FRAGMENT AND USE THEREOF 東亞合成株式会社 2025-03-27 WO disclosed
WO-2025033255-A1 PEPTIDE FRAGMENT AND USE THEREOF 東亞合成株式会社 2025-02-13 WO disclosed
EP-0438534-A1 IMMUNOREACTANT CARRIERS HAVING A NOVEL BIOCOMPATIBLE INTERMEDIATE COATING AND PROCESS OF MAKING SAME COULTER CORPORATION (US) 1991-07-31 EP disclosed
US-4981979-A IMMUNOLOGY NEORX CORPORATION (US) 1991-01-01 US disclosed
WO-1990004178-A1 IMMUNOREACTANT CARRIERS HAVING A NOVEL BIOCOMPATIBLE INTERMEDIATE COATING AND PROCESS OF MAKING SAME COULTER CORPORATION (US) 1990-04-19 WO disclosed
US-4536391-A REACTING A PLASMIN HEAVY CHAIN WITH UROKINASE IN THE PRESENCE OF A COUPLING AGENT OTSUKA PHARMACEUTICAL CO. (JP) 1985-08-20 US disclosed
EP-0109653-A2 Process for preparing urokinase complex OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1984-05-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10953073-B2 XTEN conjugate compositions and methods of making same XPA, TXLNA, NGLY1 MGLL 3726/4885TLR9 3602/4885PSMB8 610/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.