⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11018061 | 0.97 | LMNA (0.42) | — | |
| SCHEMBL17333451 | 0.88 | — | — | |
| SCHEMBL17333320 | 0.83 | — | — | |
| SCHEMBL17333560 | 0.83 | — | — | |
| SCHEMBL9505293 | 0.81 | CYP3A4 (0.40) | — | |
| SCHEMBL11373054 | 0.79 | — | — | |
| SCHEMBL12464103 | 0.76 | — | — | |
| SCHEMBL17333387 | 0.74 | MEN1 (0.47) | — | |
| SCHEMBL513584 | 0.72 | — | — | |
| SCHEMBL9426596 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0614909-B1 | Method for selective acylation of estradiol | PERMACHEM ASIA LTD (JP) | 1998-06-10 | — | — | EP | claimed |
| EP-0614909-A2 | Method for selective acylation of estradiol | PERMACHEM ASIA, LTD. (JP) | 1994-09-14 | — | — | EP | claimed |
| EP-0138153-B1 | A SELECTIVE ACYLATION PROCESS | AB LEO (SE) | 1988-11-23 | — | — | EP | claimed |
| JP-6263794-A | — | — | None | — | — | JP | disclosed |
| US-20170152347-A1 | AMIDE DENDRIMER COMPOSITIONS | GENZYME CORP (US) | 2017-06-01 | — | — | US | disclosed |
| US-20150321996-A1 | AMIDE DENDRIMER COMPOSITIONS | GENZYME CORPORATION | 2015-11-12 | — | — | US | disclosed |
| US-9066972-B2 | Amide dendrimer compositions | GENZYME CORPORATION (US) | 2015-06-30 | — | — | US | disclosed |
| US-8900560-B2 | Amide dendrimer compositions | GENZYME CORPORATION (US) | 2014-12-02 | — | — | US | disclosed |
| US-20140235724-A1 | AMIDE DENDRIMER COMPOSITIONS | GENZYME CORPORATION (US) | 2014-08-21 | — | — | US | disclosed |
| US-20130251667-A1 | AMIDE DENDRIMER COMPOSITIONS | SANOFI (FR) | 2013-09-26 | — | — | US | disclosed |
| US-8425887-B2 | Amide dendrimer compositions | GENZYME CORPORATION (US) | 2013-04-23 | — | — | US | disclosed |
| WO-2008042222-A2 | AMIDE DENDRIMER COMPOSITIONS | GENZYME CORPORATION (US) | 2008-04-10 | — | — | WO | disclosed |
| US-6762226-B2 | PHOTOSTABILITY; HEAT AND OXIDATION RESISTANCE | CIBA SPECIALTY CHEMICALS CORPORATION | 2004-07-13 | — | — | US | disclosed |
| US-20030139500-A1 | Compositions stabilized by dioxopiperazinyl derivatives | ZEDDA ALESSANDRO (IT) | 2003-07-24 | — | — | US | disclosed |
| US-20020086921-A1 | Compositions stabilized by dioxopiperazinyl derivatives | ZEDDA ALESSANDRO (IT) | 2002-07-04 | — | — | US | disclosed |
| US-5929297-A | FORMING A MIXTURE OF DIMERS, TRIMERS AND OLIGOMERS BY CONTACTING AN ALPHA-OLEFIN WITH A CATALYST SYSTEM OF BORON TRIFLUORIDE, A PROTIC PROMOTER, AND A NITROGEN COMPOUND BEING AN AMIDE, UREA, IMIDE OR CARBAMATE | BP AMOCO CORPORATION (US) | 1999-07-27 | — | — | US | disclosed |
| EP-0614909-B1 | Method for selective acylation of estradiol | PERMACHEM ASIA LTD (JP) | 1998-06-10 | — | — | EP | disclosed |
| JP-H06263794-A | METHOD FOR SELECTIVE ACYLATION OF EXTRADIOL | PERMACHEM ASIA LTD | 1994-09-20 | — | — | JP | disclosed |
| EP-0614909-A2 | Method for selective acylation of estradiol | PERMACHEM ASIA, LTD. (JP) | 1994-09-14 | — | — | EP | disclosed |
| EP-0614909-A2 | Method for selective acylation of estradiol | PERMACHEM ASIA, LTD. (JP) | 1994-09-14 | — | — | EP | disclosed |