Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3192552 | 0.95 | TDP1 (0.53) | TDP1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL1171205 | 0.84 | TDP1 (0.43) | TDP1KDM4ECHRM2CHRM4CHRM1 | |
| SCHEMBL3206581 | 0.81 | MAPK1 (0.45) | TDP1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL3209353 | 0.81 | MAPK1 (0.41) | TDP1KMT2ACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL3214147 | 0.79 | ALDH1A1 (0.42) | TDP1CYP1A2CYP2D6PKMSMN1; SMN2 | |
| SCHEMBL28272697 | 0.79 | CA12 (0.48) | KDM4EKMT2A | |
| SCHEMBL1170967 | 0.78 | TDP1 (0.47) | TDP1CHRM2CHRM4CHRM1CHRM3 | |
| Di(Hydroxyethyl)Ether SCHEMBL3207862 | 0.78 | CYP2D6 (0.42) | KDM4ECHRM2KMT2ACYP1A2CYP2D6 | |
| SCHEMBL3214203 | 0.78 | MAPK1 (0.38) | TDP1KMT2ACYP1A2CYP2D6SMN1; SMN2 | |
| SCHEMBL3212549 | 0.77 | TLR2 (0.37) | TDP1KMT2ACYP1A2CYP2D6PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029876-A1 | POLYMERIZATION ACCELERATOR, CURABLE COMPOSITION, CURED PRODUCT, AND PROCESS FOR PRODUCING THIOL COMPOUND | SHOWA DENKO K.K. (JP) | 2010-02-04 | — | — | US | disclosed |
| EP-2030989-A1 | POLYMERIZATION ACCELERATOR, CURABLE COMPOSITION, CURED PRODUCT AND METHOD FOR PRODUCING THIOL COMPOUND | Showa Denko K.K. (JP) | 2009-03-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029876-A1 | POLYMERIZATION ACCELERATOR, CURABLE COMPOSITION, CURED PRODUCT, AND PROCESS FOR PRODUCING THIOL COMPOUND | TMT1A, CCNT1, MGMT | TDP1 1248/4885KDM4E 1733/4885CHRM2 1756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.