Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 6/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.63 |
| ▸ | KCNA5 | P22460 | 6/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.63 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL947506 | 0.79 | CYP2D6 (0.66) | CYP2C19CYP2D6CYP3A4KCNH2TSHR | |
| SCHEMBL31010271 | 0.79 | KCNA5 (0.77) | CYP1A2CYP2C19CYP2D6KCNA5CYP3A4 | |
| SCHEMBL1934346 | 0.79 | MEN1 (0.66) | CYP1A2CYP2C19CYP2D6CYP2C9KCNH2 | |
| SCHEMBL28041982 | 0.78 | CYP2D6 (0.39) | CYP1A2CYP2C19CYP2D6KCNA5CYP3A4 | |
| Hydrochloric Acid SCHEMBL27495835 | 0.78 | MEN1 (0.63) | CYP1A2CYP2C19CYP2D6CYP2C9KCNH2 | |
| SCHEMBL16227210 | 0.77 | KCNA5 (1.00) | CYP1A2CYP2C19CYP2D6KCNA5CYP3A4 | |
| SCHEMBL16227209 | 0.77 | KCNA5 (1.00) | CYP1A2CYP2C19CYP2D6KCNA5CYP3A4 | |
| SCHEMBL5267415 | 0.77 | CYP2D6 (0.68) | CYP1A2CYP2C19CYP2D6KCNA5CYP3A4 | |
| SCHEMBL16226493 | 0.77 | KCNA5 (1.00) | CYP1A2CYP2C19CYP2D6KCNA5CYP3A4 | |
| Hydrochloric Acid SCHEMBL31327366 | 0.76 | CYP2D6 (0.65) | CYP1A2CYP2C19CYP2D6KCNA5CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100035863-A1 | 2 Amino-Pyrimidine Derivatives As H4 Receptor Antagonists, Processes For Preparing Them And Their Use In Pharmaceutical Compositions | UCB PHARMA, S.A. (BE) | 2010-02-11 | — | — | US | disclosed |
| US-20060264463-A1 | Chemical compounds | MEDTECH CONVERGENCE FUND, L.P. | 2006-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264463-A1 | Chemical compounds | CCR3, CCR1, CCR4 | CYP1A2 680/4885CYP2C19 1116/4885CYP2D6 1102/4885 |
| US-20100035863-A1 | 2 Amino-Pyrimidine Derivatives As H4 Receptor Antagonists, Processes For Preparing Them And Their Use In Pharmaceutical Compositions | HRH4, HRH2, HRH3 | CYP1A2 515/4885CYP2C19 321/4885CYP2D6 300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.