Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.39 |
| ▸ | ATAD2 | Q6PL18 | 3/20 | 0.39 |
| ▸ | PIM1 | P11309 | 4/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.33 |
| ▸ | QPCT | Q16769 | 1/20 | 0.32 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 2/20 | 0.31 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3726596 | 0.90 | BRD4 (0.41) | BRD4ATAD2PIM1PIM2 | |
| SCHEMBL3029211 | 0.81 | BRD4 (0.41) | BRD4ATAD2PIM1PIM2CSF1R | |
| SCHEMBL1277593 | 0.78 | BRD4 (0.41) | BRD4ATAD2PIM1PIM2CSF1R | |
| SCHEMBL1277596 | 0.78 | BRD4 (0.41) | BRD4ATAD2PIM1PIM2CSF1R | |
| SCHEMBL1278039 | 0.78 | BRD4 (0.36) | BRD4ATAD2PIM1PIM2CSF1R | |
| SCHEMBL1278037 | 0.78 | BRD4 (0.36) | BRD4ATAD2PIM1PIM2CSF1R | |
| SCHEMBL29205591 | 0.77 | CSF1R (0.51) | BRD4ATAD2PIM1PIM2CSF1R | |
| SCHEMBL3029525 | 0.77 | BRD4 (0.41) | BRD4ATAD2PIM1PIM2CSF1R | |
| SCHEMBL3025095 | 0.77 | BRD4 (0.38) | BRD4ATAD2PIM1PIM2CSF1R | |
| SCHEMBL3025091 | 0.77 | BRD4 (0.38) | BRD4ATAD2PIM1PIM2CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2220081-A2 | GLUCOKINASE ACTIVATORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE INGREDIENT | LG Life Sciences Ltd. (KR) | 2010-08-25 | — | — | EP | disclosed |
| WO-2009082152-A2 | GLUCOKINASE ACTIVATORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE INGREDIENT | LG LIFE SCIENCES LTD. (KR) | 2009-07-02 | — | — | WO | disclosed |