SCHEMBL3208577

SCHEMBL3208577

CC1=Cc2ccccc2C1c1ccccc1C=NNc1cccc2ccccc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.43
LMNA P02545 4/20 0.43
HTT P42858 2/20 0.43
MEN1 O00255 10/20 0.38
KMT2A Q03164 10/20 0.38
SMN1; SMN2 Q16637 6/20 0.38
RAB9A P51151 6/20 0.38
NPC1 O15118 5/20 0.38
GAA P10253 5/20 0.38
KDM4E B2RXH2 4/20 0.38
TDP1 Q9NUW8 4/20 0.38
SLC2A1 P11166 1/20 0.37
ALDH1A1 P00352 4/20 0.37
POLB P06746 1/20 0.37
RAD52 P43351 1/20 0.37
TAAR1 Q96RJ0 1/20 0.37
HPGD P15428 1/20 0.36
NFKB1 P19838 1/20 0.36
NFKB2 Q00653 1/20 0.36
RELA Q04206 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3216662 0.85 MAPT (0.41) MAPTLMNAHTTMEN1KMT2A
SCHEMBL3216654 0.85 MAPT (0.41) MAPTLMNAHTTMEN1KMT2A
SCHEMBL3206153 0.84 GAA (0.39) MAPTLMNAHTTMEN1KMT2A
SCHEMBL3679280 0.80 MAPT (0.47) MAPTLMNAMEN1KMT2ASMN1; SMN2
SCHEMBL3679278 0.80 MAPT (0.47) MAPTLMNAMEN1KMT2ASMN1; SMN2
SCHEMBL3199796 0.80 MEN1 (0.43) MAPTLMNAHTTMEN1KMT2A
SCHEMBL3208570 0.79 MAPT (0.47) MAPTLMNAHTTMEN1KMT2A
SCHEMBL3208564 0.79 MAPT (0.47) MAPTLMNAHTTMEN1KMT2A
SCHEMBL3199371 0.77 MAPT (0.31) MAPTLMNAHTTMEN1KMT2A
SCHEMBL3199364 0.77 MAPT (0.31) MAPTLMNAHTTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7732643-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-08 US disclosed
US-7671226-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-02 US disclosed
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME HANAOKA HIDENORI 2010-02-25 US disclosed
EP-1426379-B1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME SUMITOMO CHEMICAL CO (JP) 2009-11-11 EP disclosed
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same HANAOKA HIDENORI 2009-02-26 US disclosed
US-7439379-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL CO., LTD. (JP) 2008-10-21 US disclosed
US-20040242410-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-02 US disclosed
EP-1426379-A1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME Sumitomo Chemical Company, Limited (JP) 2004-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same C1R, C1S, AP1M1 MAPT 2641/4885LMNA 2849/4885HTT 3149/4885
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME C1R, C1S, AP1M1 MAPT 2641/4885LMNA 2849/4885HTT 3149/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.