SCHEMBL3208640

SCHEMBL3208640

CC1=C(CC(=NNc2ccc3ccccc3c2)c2ccccc2)CC=C1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.40
MAPT P10636 6/20 0.40
GAA P10253 6/20 0.40
KDM4E B2RXH2 6/20 0.40
TDP1 Q9NUW8 4/20 0.40
SMN1; SMN2 Q16637 4/20 0.40
HTT P42858 3/20 0.40
HPGD P15428 3/20 0.40
LMNA P02545 3/20 0.40
THRB P10828 1/20 0.40
APEX1 P27695 1/20 0.39
KMT2A Q03164 9/20 0.39
MEN1 O00255 8/20 0.39
CA1 P00915 4/20 0.37
CA2 P00918 4/20 0.37
CA4 P22748 3/20 0.37
CA9 Q16790 3/20 0.37
NPC1 O15118 6/20 0.37
MRGPRX4 Q96LA9 1/20 0.36
TAAR1 Q96RJ0 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3211583 0.87 GAA (0.46) ALDH1A1MAPTGAAKDM4ETDP1
SCHEMBL3199127 0.86 APEX1 (0.38) ALDH1A1MAPTGAAKDM4ETDP1
SCHEMBL3210932 0.86 ALDH1A1 (0.38) ALDH1A1MAPTGAAKDM4ETDP1
SCHEMBL3218003 0.82 ALDH1A1 (0.40) ALDH1A1MAPTGAAKDM4ETDP1
SCHEMBL3214046 0.82 ALDH1A1 (0.40) ALDH1A1MAPTGAAKDM4ETDP1
SCHEMBL3199470 0.81 ALDH1A1 (0.42) ALDH1A1MAPTGAAKDM4ETDP1
SCHEMBL3215047 0.81 MAPT (0.37) ALDH1A1MAPTGAAKDM4ETDP1
SCHEMBL3191811 0.80 MAPT (0.37) ALDH1A1MAPTGAAKDM4ETDP1
SCHEMBL3214886 0.79 KMT2A (0.40) ALDH1A1MAPTGAAKDM4ETDP1
SCHEMBL3199639 0.79 MRGPRX4 (0.40) ALDH1A1MAPTGAAKDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7732643-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-08 US disclosed
US-7671226-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-02 US disclosed
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME HANAOKA HIDENORI 2010-02-25 US disclosed
EP-1426379-B1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME SUMITOMO CHEMICAL CO (JP) 2009-11-11 EP disclosed
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same HANAOKA HIDENORI 2009-02-26 US disclosed
US-7439379-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL CO., LTD. (JP) 2008-10-21 US disclosed
US-20040242410-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-02 US disclosed
EP-1426379-A1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME Sumitomo Chemical Company, Limited (JP) 2004-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same C1R, C1S, AP1M1 ALDH1A1 1229/4885MAPT 2641/4885GAA 4642/4885
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME C1R, C1S, AP1M1 ALDH1A1 1229/4885MAPT 2641/4885GAA 4642/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.