Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 7/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ADAM33 | Q9BZ11 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3208831 | 1.00 | FFAR1 (0.54) | FFAR1MAOBMAOAADAM17S1PR1 | |
| SCHEMBL1151924 | 0.83 | FFAR1 (0.58) | FFAR1MAOBMAOAADAM17S1PR1 | |
| SCHEMBL1151928 | 0.83 | FFAR1 (0.58) | FFAR1MAOBMAOAADAM17S1PR1 | |
| SCHEMBL3214630 | 0.83 | FFAR1 (0.58) | FFAR1MAOBMAOAADAM17S1PR1 | |
| SCHEMBL1151128 | 0.76 | FFAR1 (0.58) | FFAR1MAOBMAOAS1PR1HTR2A | |
| SCHEMBL14216112 | 0.75 | NPC1 (0.65) | FFAR1MAOBMAOAADAM17S1PR1 | |
| SCHEMBL365812 | 0.75 | NPC1 (0.64) | FFAR1MAOBMAOAADAM17S1PR1 | |
| SCHEMBL540059 | 0.74 | MAOB (0.70) | MAOBMAOAS1PR1HTR2AKCNH2 | |
| SCHEMBL1152037 | 0.74 | FFAR1 (0.61) | FFAR1MAOBMAOAS1PR1HTR2A | |
| SCHEMBL1151518 | 0.74 | FFAR1 (0.58) | FFAR1MAOBMAOAADAM17S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2077987-B1 | MANDELIC ACID DERIVATIVES AND PREPARATION THEREOF | TRANSTECH PHARMA INC (US) | 2010-11-24 | — | — | EP | disclosed |
| US-20100036150-A1 | MANDELIC ACID DERIVATIVES AND PREPARATION THEREOF | TRANSTECH PHARMA, INC. | 2010-02-11 | — | — | US | disclosed |
| EP-2077987-A1 | MANDELIC ACID DERIVATIVES AND PREPARATION THEREOF | Transtech Pharma, Inc. (US) | 2009-07-15 | — | — | EP | disclosed |
| WO-2008051563-A1 | MANDELIC ACID DERIVATIVES AND PREPARATION THEREOF | TRANSTECH PHARMA, INC. (US) | 2008-05-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100036150-A1 | MANDELIC ACID DERIVATIVES AND PREPARATION THEREOF | CYP8B1, CYP51A1, COMT | FFAR1 1313/4885MAOB 85/4885MAOA 56/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.