SCHEMBL320903

SCHEMBL320903

COCOc1ccc(Cl)c(F)c1

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.43
SLC6A4 P31645 5/20 0.42
HTR2A P28223 3/20 0.42
KCNH2 Q12809 3/20 0.42
ATF4 P18848 4/20 0.40
HRH3 Q9Y5N1 1/20 0.40
PPARG P37231 1/20 0.40
PPARA Q07869 1/20 0.40
HTR7 P34969 3/20 0.39
HTR1A P08908 2/20 0.39
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37
MCL1 Q07820 1/20 0.37
FFAR1 O14842 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30954109 1.00 GPR84 (0.43) GPR84SLC6A4HTR2AKCNH2ATF4
SCHEMBL19816715 0.85 MAPT (0.44) SLC6A4HTR2AKCNH2MAOB
SCHEMBL8123834 0.82 MAOB (0.45) SLC6A4HTR2AMAOAMAOBFFAR1
SCHEMBL15114753 0.82 KDM4E (0.50) GPR84SLC6A4HTR2AKCNH2
SCHEMBL31697317 0.82 MAOB (0.45) SLC6A4HTR2AMAOAMAOBFFAR1
SCHEMBL2010983 0.81 NQO1 (0.50) GPR84SLC6A4HTR2AKCNH2ATF4
SCHEMBL10218896 0.79 MCL1 (0.57) GPR84MCL1
SCHEMBL8124711 0.79 MRGPRX4 (0.46) SLC6A4PPARGMAOBFFAR1
SCHEMBL276095 0.78 CYP1A2 (0.46) SLC6A4HTR2AKCNH2PPARGPPARA
SCHEMBL29590981 0.78 CYP1A2 (0.46) SLC6A4HTR2AKCNH2PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630412-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD Pharma A/S (DK) 2025-10-15 EP disclosed
WO-2024121130-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2024-06-13 WO disclosed
WO-2024121130-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2024-06-13 WO disclosed
EP-2590955-A1 SPIRO-CYCLIC AMINE DERIVATIVES AS S1P MODULATORS ABBVIE B.V. (NL) 2013-05-15 EP disclosed
WO-2012004378-A1 SPIRO-CYCLIC AMINE DERIVATIVES AS S1P MODULATORS ABBOTT HEALTHCARE PRODUCTS B.V. (NL) 2012-01-12 WO disclosed
US-7259266-B2 Benzopyran compounds useful for treating inflammatory conditions PHARMACIA CORPORATION (US) 2007-08-21 US disclosed
US-7259266-B2 Benzopyran compounds useful for treating inflammatory conditions PHARMACIA CORPORATION (US) 2007-08-21 US disclosed