Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 10/20 | 1.00 |
| ▸ | MAPT | P10636 | 3/20 | 0.80 |
| ▸ | APP | P05067 | 2/20 | 0.80 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.74 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.74 |
| ▸ | TUBB | P07437 | 3/20 | 0.74 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.74 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.74 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.74 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.74 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.74 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.74 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.74 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.74 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.74 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.74 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.74 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.74 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.74 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3209544 | 1.00 | BACE1 (1.00) | BACE1MAPTAPPTUBB1TUBB4A | |
| SCHEMBL2622437 | 0.92 | MAPT (0.89) | BACE1MAPTAPPABCB1MEN1 | |
| SCHEMBL5599057 | 0.92 | MAPT (0.89) | BACE1MAPTAPPABCB1MEN1 | |
| SCHEMBL3221583 | 0.90 | BACE1 (0.82) | BACE1MAPTAPPTUBB1ABCB1 | |
| SCHEMBL3221636 | 0.90 | BACE1 (0.82) | BACE1MAPTAPPTUBB1ABCB1 | |
| SCHEMBL3223971 | 0.90 | APP (0.86) | BACE1MAPTAPPTUBB1TUBB4A | |
| SCHEMBL3223922 | 0.90 | APP (0.86) | BACE1MAPTAPPTUBB1TUBB4A | |
| SCHEMBL3221529 | 0.89 | BACE1 (0.80) | BACE1MAPTAPPABCB1MEN1 | |
| SCHEMBL3222140 | 0.89 | APP (1.00) | BACE1MAPTAPPABCB1MEN1 | |
| SCHEMBL3222158 | 0.89 | APP (1.00) | BACE1MAPTAPPABCB1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962674-B2 | Curcumin derivative | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2015-02-24 | — | — | US | disclosed |
| US-20100048901-A1 | NOVEL CURCUMIN DERIVATIVE | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2010-02-25 | — | — | US | disclosed |
| EP-2123637-A1 | NOVEL CURCUMIN DERIVATIVE | Tokyo Institute of Technology (JP) | 2009-11-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048901-A1 | NOVEL CURCUMIN DERIVATIVE | BACE1, APP, BACE2 | BACE1 1/4885MAPT 8/4885APP 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.