Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 19/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.55 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9805806 | 0.86 | VCAM1 (0.65) | VCAM1ALDH1A1NPBWR1MCHR1 | |
| SCHEMBL1097803 | 0.82 | VCAM1 (0.69) | VCAM1ALDH1A1NPBWR1MCHR1 | |
| SCHEMBL11546879 | 0.82 | VCAM1 (0.50) | VCAM1ALDH1A1 | |
| SCHEMBL30813055 | 0.82 | VCAM1 (0.69) | VCAM1ALDH1A1NPBWR1MCHR1 | |
| SCHEMBL9404105 | 0.82 | VCAM1 (0.63) | VCAM1ALDH1A1NPBWR1MCHR1 | |
| Butane SCHEMBL9586852 | 0.82 | VCAM1 (0.84) | VCAM1ALDH1A1 | |
| SCHEMBL809482 | 0.82 | VCAM1 (0.73) | VCAM1ALDH1A1NPBWR1MCHR1 | |
| SCHEMBL10452716 | 0.82 | VCAM1 (0.73) | VCAM1ALDH1A1NPBWR1MCHR1 | |
| SCHEMBL29780388 | 0.82 | VCAM1 (0.73) | VCAM1ALDH1A1NPBWR1MCHR1 | |
| SCHEMBL5471880 | 0.81 | VCAM1 (1.00) | VCAM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105566182-A | Synthetic method of 2-amino-4-(ethylsulfonyl) phenol | SUZHOU TIANMA SPECIALTY CHEMICALS CO LTD | 2016-05-11 | — | — | CN | claimed |
| US-20180280319-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATMENT OF BREAST CANCER | UNIVERSITY OF THE SCIENCES | 2018-10-04 | — | — | US | disclosed |
| CN-105566182-B | A kind of 2 amino 4（Ethylsulfonyl）The synthetic method of phenol | 苏州天马精细化学品股份有限公司 | 2018-02-13 | — | — | CN | disclosed |
| US-20170121322-A1 | BET-PROTEIN INHIBITING 3,4-DIHYDROPYRIDO[2,3-B]PYRAZINONES WITH META-SUBSTITUTED AROMATIC AMINO- OR ETHER GROUPS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-05-04 | — | — | US | disclosed |
| EP-3157919-A1 | BET-PROTEIN INHIBITING 3,4-DIHYDROPYRIDO[2,3-B]PYRAZINONES WITH META-SUBSTITUTED AROMATIC AMINO- OR ETHER GROUPS | Bayer Pharma Aktiengesellschaft (DE) | 2017-04-26 | — | — | EP | disclosed |
| CN-106573931-A | Bet-protein inhibiting 3,4-dihydropyrido[2,3-b]pyrazinones with meta-substituted aromatic amino- or ether groups | 拜耳医药股份有限公司 | 2017-04-19 | — | — | CN | disclosed |
| CN-105566182-A | Synthetic method of 2-amino-4-(ethylsulfonyl) phenol | SUZHOU TIANMA SPECIALTY CHEMICALS CO LTD | 2016-05-11 | — | — | CN | disclosed |
| CN-105566182-A | Synthetic method of 2-amino-4-(ethylsulfonyl) phenol | SUZHOU TIANMA SPECIALTY CHEMICALS CO LTD | 2016-05-11 | — | — | CN | disclosed |
| WO-2015193219-A1 | BET-PROTEIN INHIBITING 3,4-DIHYDROPYRIDO[2,3-B]PYRAZINONES WITH META-SUBSTITUTED AROMATIC AMINO- OR ETHER GROUPS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-12-23 | — | — | WO | disclosed |
| EP-2142531-B1 | BENZIMIDAZOLE CANNABINOID AGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2015-07-08 | — | — | EP | disclosed |
| EP-1809607-A1 | SULFONYL BENZIMIDAZOLE DERIVATIVES | Pfizer, Inc. (US) | 2007-07-25 | — | — | EP | disclosed |
| WO-2006048754-A1 | SULFONYL BENZIMIDAZOLE DERIVATIVES | PFIZER JAPAN INC. (JP) | 2006-05-11 | — | — | WO | disclosed |
| US-20060094750-A1 | Sulfonyl benzimidazole derivatives | KON-I KANA | 2006-05-04 | — | — | US | disclosed |
| EP-0116827-B1 | PROCESS FOR THE PREPARATION OF BENZOTHIAZOLES | BAYER AG (DE) | 1991-04-10 | — | — | EP | disclosed |
| US-4918183-A | Monoazo dyes, process for their preparation, and the use thereof | CIBA-GEIGY CORPORATION (US) | 1990-04-17 | — | — | US | disclosed |
| US-4906740-A | Monoazo dyes containing as the azo component A phenylsulfonylphenyl radical | CIBA-GEIGY CORPORATION (US) | 1990-03-06 | — | — | US | disclosed |
| US-4808723-A | Process for the preparation of benzothiazoles | BAYER AKTIENGESELLSCHAFT (DE) | 1989-02-28 | — | — | US | disclosed |
| EP-0116827-A2 | Process for the preparation of benzothiazoles | BAYER AG (DE) | 1984-08-29 | — | — | EP | disclosed |
| EP-0010249-A2 | Herbicidal agents, process for their preparation and their use in combating weeds | BAYER AG (DE) | 1980-04-30 | — | — | EP | disclosed |
| EP-0010250-A2 | Use of Sulfonanilides in inhibition of plant growth | BAYER AG (DE) | 1980-04-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180280319-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATMENT OF BREAST CANCER | BRCA1, ANXA5, ANXA3 | VCAM1 3869/4885ALDH1A1 811/4885NPBWR1 4590/4885 |
| US-20170121322-A1 | BET-PROTEIN INHIBITING 3,4-DIHYDROPYRIDO[2,3-B]PYRAZINONES WITH META-SUBSTITUTED AROMATIC AMINO- OR ETHER GROUPS | BRD4, BRDT, BRD3 | VCAM1 2981/4885ALDH1A1 4715/4885NPBWR1 3612/4885 |
| US-20060094750-A1 | Sulfonyl benzimidazole derivatives | TRPV1, CNR2, CNR1 | VCAM1 293/4885ALDH1A1 2810/4885NPBWR1 201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.