Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 11/20 | 0.60 |
| ▸ | CCR9 | P51686 | 6/20 | 0.57 |
| ▸ | CNR1 | P21554 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3209376 | 0.88 | CNR1 (0.49) | CCR2CCR9CNR1 | |
| SCHEMBL3198956 | 0.86 | CCR2 (0.64) | CCR2CNR1 | |
| SCHEMBL3204203 | 0.86 | CCR2 (0.73) | CCR2CCR9CNR1 | |
| SCHEMBL3202063 | 0.85 | CCR2 (0.62) | CCR2CCR9CNR1 | |
| SCHEMBL3201861 | 0.85 | CNR1 (0.69) | CCR2CCR9CNR1 | |
| SCHEMBL13422677 | 0.84 | CNR1 (0.75) | CCR2CNR1 | |
| SCHEMBL3201659 | 0.83 | CCR2 (0.62) | CCR2CNR1 | |
| SCHEMBL3200970 | 0.80 | CNR1 (0.70) | CCR2CNR1 | |
| SCHEMBL3205608 | 0.75 | CCR2 (0.63) | CCR2CCR9 | |
| SCHEMBL6306888 | 0.75 | CCR2 (0.79) | CCR2CCR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7671080-B2 | 1-benzylindole-2-carboxamide derivatives | N.V. ORGANON (NL) | 2010-03-02 | — | — | US | disclosed |
| US-20080280923-A1 | 1-Benzylindole-2-Carboxamide Derivatives | N.V. ORGANON (NL) | 2008-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080280923-A1 | 1-Benzylindole-2-Carboxamide Derivatives | CNR2, CNR1, HTR2C | CCR2 830/4885CCR9 3642/4885CNR1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.