SCHEMBL3210233

SCHEMBL3210233

CC1=C(C)C(C)C(c2ccccc2CNc2c(C)cc(C)cc2C)=C1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.42
MAPT P10636 11/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
TP53 P04637 1/20 0.33
MEN1 O00255 5/20 0.32
KMT2A Q03164 5/20 0.32
NPC1 O15118 1/20 0.32
ALDH1A1 P00352 4/20 0.31
NPSR1 Q6W5P4 4/20 0.31
MAPK1 P28482 3/20 0.31
POLB P06746 3/20 0.31
HPGD P15428 3/20 0.31
TDP1 Q9NUW8 3/20 0.31
NSD2 O96028 2/20 0.31
THRB P10828 2/20 0.31
RECQL P46063 2/20 0.31
P2RY1 P47900 2/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
FFAR4 Q5NUL3 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3202886 0.85 MAPT (0.40) GAAMAPTSMN1; SMN2MEN1KMT2A
SCHEMBL3202741 0.83 MAPT (0.32) MAPTALDH1A1MAPK1
SCHEMBL3191285 0.82 GAA (0.42) GAAMAPTSMN1; SMN2TP53MEN1
SCHEMBL3211474 0.81 MAPT (0.36) GAAMAPTSMN1; SMN2MEN1KMT2A
SCHEMBL3203195 0.81 FFAR1 (0.40) GAAMAPTSMN1; SMN2MEN1KMT2A
Hydrochloric Acid SCHEMBL3259820 0.80
SCHEMBL3206098 0.80 USP1 (0.36) SMN1; SMN2MEN1KMT2A
SCHEMBL3203974 0.78 MEN1 (0.38) GAAMAPTMEN1KMT2AALDH1A1
SCHEMBL3203613 0.75 HTT (0.35) GAAMEN1KMT2AALDH1A1HPGD
Hydrochloric Acid SCHEMBL3259818 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7732643-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-08 US disclosed
US-7671226-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-02 US disclosed
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME HANAOKA HIDENORI 2010-02-25 US disclosed
EP-1426379-B1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME SUMITOMO CHEMICAL CO (JP) 2009-11-11 EP disclosed
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same HANAOKA HIDENORI 2009-02-26 US disclosed
US-7439379-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL CO., LTD. (JP) 2008-10-21 US disclosed
US-20040242410-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-02 US disclosed
EP-1426379-A1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME Sumitomo Chemical Company, Limited (JP) 2004-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same C1R, C1S, AP1M1 GAA 4642/4885MAPT 2641/4885SMN1; SMN2 3599/4885
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME C1R, C1S, AP1M1 GAA 4642/4885MAPT 2641/4885SMN1; SMN2 3599/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.