SCHEMBL3210769

SCHEMBL3210769

CCOC(=O)C(=N)OC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL554111 0.84 ALDH1A1 (0.48)
Hydrochloric Acid SCHEMBL2935026 0.82 ALDH1A1 (0.46)
SCHEMBL11114893 0.80
SCHEMBL8650798 0.78
Hydrochloric Acid SCHEMBL6640631 0.78 GAA (0.44)
SCHEMBL11121210 0.78 ALDH1A1 (0.50)
SCHEMBL21737763 0.78 NPSR1 (0.46)
SCHEMBL15884500 0.76 CYP2D6 (0.47)
SCHEMBL129683 0.76
SCHEMBL9397896 0.76 ALDH1A1 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0052819-B1 PROCESS FOR PREPARING AMIDINECARBOXYLIC ACIDS UBE INDUSTRIES, LTD. (JP) 1984-02-29 EP claimed
US-4375554-A REACTING AN ALKOXYIMINOACETIC ACID ESTER WITH A PRIMARY AMINE UBE INDUSTRIES LTD. (JP) 1983-03-01 US claimed
EP-0052819-A1 Process for preparing amidinecarboxylic acids UBE INDUSTRIES, LTD. (JP) 1982-06-02 EP claimed
JP-57085352-A None JP disclosed
JP-57085351-A None JP disclosed
CN-103012313-A Synthetic method of aminothiazoly loximate SHANDONG XINQUAN PHARMACEUTICAL CO LTD 2013-04-03 CN disclosed
US-7683097-B2 Topoisomerase inhibitors Propharmacon Inc. (US) 2010-03-23 US disclosed
US-20070004701-A1 Topoisomerase inhibitors PROPHARMACON, INC. (US) 2007-01-04 US disclosed
EP-0052819-B1 PROCESS FOR PREPARING AMIDINECARBOXYLIC ACIDS UBE INDUSTRIES, LTD. (JP) 1984-02-29 EP disclosed
US-4375554-A REACTING AN ALKOXYIMINOACETIC ACID ESTER WITH A PRIMARY AMINE UBE INDUSTRIES LTD. (JP) 1983-03-01 US disclosed
EP-0052819-A1 Process for preparing amidinecarboxylic acids UBE INDUSTRIES, LTD. (JP) 1982-06-02 EP disclosed
JP-S5785352-A PREPARATION OF N-ARYLAMIDINECARBOXYLIC ACID UBE IND LTD 1982-05-28 JP disclosed
JP-S5785351-A PREPARATION OF AMIDINECARBOXYLIC ACID UBE IND LTD 1982-05-28 JP disclosed